Down-regulation of PU.1 by methylation of distal regulatory elements and the promoter is required for myeloma cell growth

• Main Authors: Tatetsu, H, Ueno, S, Hata, H, Yamada, Y, Takeya, M, Mitsuya, H, Tenen, D.G, Okuno, Y
• Other Authors: MEDICINE
• Format: Article
• Published: 2020
• Subjects: 5 aza 2' deoxycytidine; deoxyribonuclease I; transcription factor PU 1; article; cancer cell culture; cancer survival; cell death; cell isolation; controlled study; demethylation; down regulation; growth disorder; human; human cell; hypersensitivity reaction; methylation; myeloma cell; plasma cell; priority journal; prognosis; promoter region; protein expression; tumor growth; upregulation; Apoptosis; Azacitidine; Base Sequence; Cell Growth Processes; Cell Line, Tumor; DNA Methylation; Down-Regulation; Gene Expression Regulation, Neoplastic; Humans; Introns; Molecular Sequence Data; Multiple Myeloma; Prognosis; Promoter Regions (Genetics); Proto-Oncogene Proteins; Regulatory Elements, Transcriptional; Trans-Activators; Up-Regulation
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/181036
• Institution: National University of Singapore

10.1158/0008-5472.CAN-06-4265