Mutational Mtc6p attenuates autophagy and improves secretory expression of heterologous proteins in Kluyveromyces marxianus 06 Biological Sciences 0601 Biochemistry and Cell Biology

• Main Authors: Liu, Y, Mo, W.-J, Shi, T.-F, Wang, M.-Z, Zhou, J.-G, Yu, Y, Yew, W.-S, Lu, H
• Other Authors: DEPT OF BIOCHEMISTRY
• Format: Article
• Published: 2020
• Subjects: beta mannosidase; CRISPR associated protein; cytosine; endo 1,4 beta xylanase; esterase; fungal protein; monocarboxylate transporter 6; Mtc6p protein; ruminal feruloyl esterase; tyrosine; unclassified drug; bacterial protein; Article; autophagy; controlled study; CRISPR-CAS9 system; endoplasmic reticulum; fungus mutant; gamma irradiation; gene deletion; gene editing; gene mutation; gene targeting; genetic transcription; heterologous expression; Kluyveromyces marxianus; Mtc6p gene; nonhuman; open reading frame; protein expression; protein folding; protein secretion; radiation mutagenesis; reporter gene; ultraviolet radiation; whole genome sequencing; bacterial gene; biosynthesis; genetics; Kluyveromyces; metabolic engineering; metabolism; physiology; Autophagy; Bacterial Proteins; Esterases; Gene Editing; Genes, Bacterial; Metabolic Engineering; Whole Genome Sequencing
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/181179
• Institution: National University of Singapore

10.1186/s12934-018-0993-9