Breast cancer stem-like cells are inhibited by diosgenin, a steroidal saponin, by the attenuation of the Wnt β-catenin signaling via the Wnt antagonist secreted frizzled related protein-4

10.3389/fphar.2017.00124

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Main Authors:	Bhuvanalakshmi, G, Basappa, Laboratory of Chemical Biology, Department of Chemistry, Bangalore University, Bangalore, India, Rangappa, K.S, Dharmarajan, A, Sethi, G, Kumar, A.P, Warrier, S
Other Authors:	DEPT OF PHARMACOLOGY
Format:	Article
Published:	2020
Subjects:	aldehyde dehydrogenase beta catenin caspase 3 caspase 7 diosgenin glycogen synthase kinase 3beta Hermes antigen reactive oxygen metabolite secreted frizzled related protein 4 Wnt protein antiangiogenic activity antineoplastic activity antiproliferative activity apoptosis Article breast cancer cell line cancer inhibition cancer stem cell cell cycle checkpoint cell self-renewal chick controlled study drug efficacy embryo epithelial mesenchymal transition G0 phase cell cycle checkpoint gene expression loss of function mutation migration inhibition nonhuman protein expression Wnt signaling pathway
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/181291
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Institution:	National University of Singapore

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spelling	sg-nus-scholar.10635-1812912023-10-31T09:13:47Z Breast cancer stem-like cells are inhibited by diosgenin, a steroidal saponin, by the attenuation of the Wnt β-catenin signaling via the Wnt antagonist secreted frizzled related protein-4 Bhuvanalakshmi, G Basappa, Laboratory of Chemical Biology, Department of Chemistry, Bangalore University, Bangalore, India Rangappa, K.S Dharmarajan, A Sethi, G Kumar, A.P Warrier, S DEPT OF PHARMACOLOGY aldehyde dehydrogenase beta catenin caspase 3 caspase 7 diosgenin glycogen synthase kinase 3beta Hermes antigen reactive oxygen metabolite secreted frizzled related protein 4 Wnt protein antiangiogenic activity antineoplastic activity antiproliferative activity apoptosis Article breast cancer cell line cancer inhibition cancer stem cell cell cycle checkpoint cell self-renewal chick controlled study drug efficacy embryo epithelial mesenchymal transition G0 phase cell cycle checkpoint gene expression loss of function mutation migration inhibition nonhuman protein expression Wnt signaling pathway 10.3389/fphar.2017.00124 Frontiers in Pharmacology 8 MAR 124 2020-10-27T10:28:43Z 2020-10-27T10:28:43Z 2017 Article Bhuvanalakshmi, G, Basappa, Laboratory of Chemical Biology, Department of Chemistry, Bangalore University, Bangalore, India, Rangappa, K.S, Dharmarajan, A, Sethi, G, Kumar, A.P, Warrier, S (2017). Breast cancer stem-like cells are inhibited by diosgenin, a steroidal saponin, by the attenuation of the Wnt β-catenin signaling via the Wnt antagonist secreted frizzled related protein-4. Frontiers in Pharmacology 8 (MAR) : 124. ScholarBank@NUS Repository. https://doi.org/10.3389/fphar.2017.00124 16639812 https://scholarbank.nus.edu.sg/handle/10635/181291 Attribution 4.0 International http://creativecommons.org/licenses/by/4.0/ Unpaywall 20201031
institution	National University of Singapore
building	NUS Library
continent	Asia
country	Singapore Singapore
content_provider	NUS Library
collection	ScholarBank@NUS
topic	aldehyde dehydrogenase beta catenin caspase 3 caspase 7 diosgenin glycogen synthase kinase 3beta Hermes antigen reactive oxygen metabolite secreted frizzled related protein 4 Wnt protein antiangiogenic activity antineoplastic activity antiproliferative activity apoptosis Article breast cancer cell line cancer inhibition cancer stem cell cell cycle checkpoint cell self-renewal chick controlled study drug efficacy embryo epithelial mesenchymal transition G0 phase cell cycle checkpoint gene expression loss of function mutation migration inhibition nonhuman protein expression Wnt signaling pathway
spellingShingle	aldehyde dehydrogenase beta catenin caspase 3 caspase 7 diosgenin glycogen synthase kinase 3beta Hermes antigen reactive oxygen metabolite secreted frizzled related protein 4 Wnt protein antiangiogenic activity antineoplastic activity antiproliferative activity apoptosis Article breast cancer cell line cancer inhibition cancer stem cell cell cycle checkpoint cell self-renewal chick controlled study drug efficacy embryo epithelial mesenchymal transition G0 phase cell cycle checkpoint gene expression loss of function mutation migration inhibition nonhuman protein expression Wnt signaling pathway Bhuvanalakshmi, G Basappa, Laboratory of Chemical Biology, Department of Chemistry, Bangalore University, Bangalore, India Rangappa, K.S Dharmarajan, A Sethi, G Kumar, A.P Warrier, S Breast cancer stem-like cells are inhibited by diosgenin, a steroidal saponin, by the attenuation of the Wnt β-catenin signaling via the Wnt antagonist secreted frizzled related protein-4
description	10.3389/fphar.2017.00124
author2	DEPT OF PHARMACOLOGY
author_facet	DEPT OF PHARMACOLOGY Bhuvanalakshmi, G Basappa, Laboratory of Chemical Biology, Department of Chemistry, Bangalore University, Bangalore, India Rangappa, K.S Dharmarajan, A Sethi, G Kumar, A.P Warrier, S
format	Article
author	Bhuvanalakshmi, G Basappa, Laboratory of Chemical Biology, Department of Chemistry, Bangalore University, Bangalore, India Rangappa, K.S Dharmarajan, A Sethi, G Kumar, A.P Warrier, S
author_sort	Bhuvanalakshmi, G
title	Breast cancer stem-like cells are inhibited by diosgenin, a steroidal saponin, by the attenuation of the Wnt β-catenin signaling via the Wnt antagonist secreted frizzled related protein-4
title_short	Breast cancer stem-like cells are inhibited by diosgenin, a steroidal saponin, by the attenuation of the Wnt β-catenin signaling via the Wnt antagonist secreted frizzled related protein-4
title_full	Breast cancer stem-like cells are inhibited by diosgenin, a steroidal saponin, by the attenuation of the Wnt β-catenin signaling via the Wnt antagonist secreted frizzled related protein-4
title_fullStr	Breast cancer stem-like cells are inhibited by diosgenin, a steroidal saponin, by the attenuation of the Wnt β-catenin signaling via the Wnt antagonist secreted frizzled related protein-4
title_full_unstemmed	Breast cancer stem-like cells are inhibited by diosgenin, a steroidal saponin, by the attenuation of the Wnt β-catenin signaling via the Wnt antagonist secreted frizzled related protein-4
title_sort	breast cancer stem-like cells are inhibited by diosgenin, a steroidal saponin, by the attenuation of the wnt β-catenin signaling via the wnt antagonist secreted frizzled related protein-4
publishDate	2020
url	https://scholarbank.nus.edu.sg/handle/10635/181291
_version_	1781792467491749888

Breast cancer stem-like cells are inhibited by diosgenin, a steroidal saponin, by the attenuation of the Wnt β-catenin signaling via the Wnt antagonist secreted frizzled related protein-4

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