Of mice and CRISPR: The post-CRISPR future of the mouse as a model system for the human condition

• Main Authors: Liu, E.T, Bolcun-Filas, E, Grass, D.S, Lutz, C, Murray, S, Shultz, L, Rosenthal, N
• Other Authors: MEDICINE
• Format: Note
• Published: 2020
• Subjects: double stranded DNA; guide RNA; clustered regularly interspaced short palindromic repeat; cost control; CRISPR Cas system; experimental model; gene editing; gene targeting; genetic model; genetic variability; high throughput sequencing; homologous recombination; human; human genome; molecular cloning; mouse; mouse embryonic stem cell; nonhuman; Note; priority journal; reproducibility; standardization; transgenics; animal; disease model; genetic engineering; genetics; procedures; trends; Animals; CRISPR-Cas Systems; Disease Models, Animal; Genetic Engineering; Humans; Mice
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/181301
• Institution: National University of Singapore

10.15252/embr.201643717