Bevacizumab and Combination Chemotherapy in rectal cancer Until Surgery (BACCHUS): A phase II, multicentre, open-label, randomised study of neoadjuvant chemotherapy alone in patients with high-risk cancer of the rectum

10.1186/s12885-015-1764-1

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Main Authors:	Glynne-Jones, R, Hava, N, Goh, V, Bosompem, S, Bridgewater, J, Chau, I, Gaya, A, Wasan, H, Moran, B, Melcher, L, MacDonald, A, Osborne, M, Beare, S, Jitlal, M, Lopes, A, Hall, M, West, N, Quirke, P, Wong, W.-L, Harrison, M, and for the Bacchus investigato
Other Authors:	SURGERY
Format:	Article
Published:	2020
Subjects:	bevacizumab fluorouracil folinic acid irinotecan oxaliplatin angiogenesis inhibitor antineoplastic agent advanced cancer Article cancer adjuvant therapy cancer combination chemotherapy cancer control cancer grading cancer prognosis cancer regression cancer size cancer staging colostomy computer assisted emission tomography continuous infusion controlled study disease free survival drug efficacy drug monitoring drug safety drug tolerability feasibility study follow up high risk patient histopathology human human tissue multicenter study multiple cycle treatment nuclear magnetic resonance imaging open study outcome assessment overall survival patient compliance phase 2 clinical trial preoperative treatment progression free survival prospective study randomized controlled trial rectum cancer rectum surgery total mesorectal excision treatment response abdominal surgery adjuvant chemotherapy aged clinical trial combination drug therapy female male neoadjuvant therapy prognosis Rectal Neoplasms treatment outcome Aged Angiogenesis Inhibitors Antineoplastic Agents Bevacizumab Chemotherapy, Adjuvant Digestive System Surgical Procedures Drug Therapy, Combination Female Humans Male Neoadjuvant Therapy Prognosis Prospective Studies Treatment Outcome
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/181427
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Institution:	National University of Singapore

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spelling	sg-nus-scholar.10635-1814272024-04-25T02:38:08Z Bevacizumab and Combination Chemotherapy in rectal cancer Until Surgery (BACCHUS): A phase II, multicentre, open-label, randomised study of neoadjuvant chemotherapy alone in patients with high-risk cancer of the rectum Glynne-Jones, R Hava, N Goh, V Bosompem, S Bridgewater, J Chau, I Gaya, A Wasan, H Moran, B Melcher, L MacDonald, A Osborne, M Beare, S Jitlal, M Lopes, A Hall, M West, N Quirke, P Wong, W.-L Harrison, M and for the Bacchus investigato SURGERY bevacizumab fluorouracil folinic acid irinotecan oxaliplatin angiogenesis inhibitor antineoplastic agent bevacizumab advanced cancer Article cancer adjuvant therapy cancer combination chemotherapy cancer control cancer grading cancer prognosis cancer regression cancer size cancer staging colostomy computer assisted emission tomography continuous infusion controlled study disease free survival drug efficacy drug monitoring drug safety drug tolerability feasibility study follow up high risk patient histopathology human human tissue multicenter study multiple cycle treatment nuclear magnetic resonance imaging open study outcome assessment overall survival patient compliance phase 2 clinical trial preoperative treatment progression free survival prospective study randomized controlled trial rectum cancer rectum surgery total mesorectal excision treatment response abdominal surgery adjuvant chemotherapy aged clinical trial combination drug therapy female male neoadjuvant therapy prognosis Rectal Neoplasms treatment outcome Aged Angiogenesis Inhibitors Antineoplastic Agents Bevacizumab Chemotherapy, Adjuvant Digestive System Surgical Procedures Drug Therapy, Combination Female Humans Male Neoadjuvant Therapy Prognosis Prospective Studies Rectal Neoplasms Treatment Outcome 10.1186/s12885-015-1764-1 BMC Cancer 15 1 764 2020-10-27T10:53:29Z 2020-10-27T10:53:29Z 2015 Article Glynne-Jones, R, Hava, N, Goh, V, Bosompem, S, Bridgewater, J, Chau, I, Gaya, A, Wasan, H, Moran, B, Melcher, L, MacDonald, A, Osborne, M, Beare, S, Jitlal, M, Lopes, A, Hall, M, West, N, Quirke, P, Wong, W.-L, Harrison, M, and for the Bacchus investigato (2015). Bevacizumab and Combination Chemotherapy in rectal cancer Until Surgery (BACCHUS): A phase II, multicentre, open-label, randomised study of neoadjuvant chemotherapy alone in patients with high-risk cancer of the rectum. BMC Cancer 15 (1) : 764. ScholarBank@NUS Repository. https://doi.org/10.1186/s12885-015-1764-1 14712407 https://scholarbank.nus.edu.sg/handle/10635/181427 Attribution 4.0 International http://creativecommons.org/licenses/by/4.0/ Unpaywall 20201031
institution	National University of Singapore
building	NUS Library
continent	Asia
country	Singapore Singapore
content_provider	NUS Library
collection	ScholarBank@NUS
topic	bevacizumab fluorouracil folinic acid irinotecan oxaliplatin angiogenesis inhibitor antineoplastic agent bevacizumab advanced cancer Article cancer adjuvant therapy cancer combination chemotherapy cancer control cancer grading cancer prognosis cancer regression cancer size cancer staging colostomy computer assisted emission tomography continuous infusion controlled study disease free survival drug efficacy drug monitoring drug safety drug tolerability feasibility study follow up high risk patient histopathology human human tissue multicenter study multiple cycle treatment nuclear magnetic resonance imaging open study outcome assessment overall survival patient compliance phase 2 clinical trial preoperative treatment progression free survival prospective study randomized controlled trial rectum cancer rectum surgery total mesorectal excision treatment response abdominal surgery adjuvant chemotherapy aged clinical trial combination drug therapy female male neoadjuvant therapy prognosis Rectal Neoplasms treatment outcome Aged Angiogenesis Inhibitors Antineoplastic Agents Bevacizumab Chemotherapy, Adjuvant Digestive System Surgical Procedures Drug Therapy, Combination Female Humans Male Neoadjuvant Therapy Prognosis Prospective Studies Rectal Neoplasms Treatment Outcome
spellingShingle	bevacizumab fluorouracil folinic acid irinotecan oxaliplatin angiogenesis inhibitor antineoplastic agent bevacizumab advanced cancer Article cancer adjuvant therapy cancer combination chemotherapy cancer control cancer grading cancer prognosis cancer regression cancer size cancer staging colostomy computer assisted emission tomography continuous infusion controlled study disease free survival drug efficacy drug monitoring drug safety drug tolerability feasibility study follow up high risk patient histopathology human human tissue multicenter study multiple cycle treatment nuclear magnetic resonance imaging open study outcome assessment overall survival patient compliance phase 2 clinical trial preoperative treatment progression free survival prospective study randomized controlled trial rectum cancer rectum surgery total mesorectal excision treatment response abdominal surgery adjuvant chemotherapy aged clinical trial combination drug therapy female male neoadjuvant therapy prognosis Rectal Neoplasms treatment outcome Aged Angiogenesis Inhibitors Antineoplastic Agents Bevacizumab Chemotherapy, Adjuvant Digestive System Surgical Procedures Drug Therapy, Combination Female Humans Male Neoadjuvant Therapy Prognosis Prospective Studies Rectal Neoplasms Treatment Outcome Glynne-Jones, R Hava, N Goh, V Bosompem, S Bridgewater, J Chau, I Gaya, A Wasan, H Moran, B Melcher, L MacDonald, A Osborne, M Beare, S Jitlal, M Lopes, A Hall, M West, N Quirke, P Wong, W.-L Harrison, M and for the Bacchus investigato Bevacizumab and Combination Chemotherapy in rectal cancer Until Surgery (BACCHUS): A phase II, multicentre, open-label, randomised study of neoadjuvant chemotherapy alone in patients with high-risk cancer of the rectum
description	10.1186/s12885-015-1764-1
author2	SURGERY
author_facet	SURGERY Glynne-Jones, R Hava, N Goh, V Bosompem, S Bridgewater, J Chau, I Gaya, A Wasan, H Moran, B Melcher, L MacDonald, A Osborne, M Beare, S Jitlal, M Lopes, A Hall, M West, N Quirke, P Wong, W.-L Harrison, M and for the Bacchus investigato
format	Article
author	Glynne-Jones, R Hava, N Goh, V Bosompem, S Bridgewater, J Chau, I Gaya, A Wasan, H Moran, B Melcher, L MacDonald, A Osborne, M Beare, S Jitlal, M Lopes, A Hall, M West, N Quirke, P Wong, W.-L Harrison, M and for the Bacchus investigato
author_sort	Glynne-Jones, R
title	Bevacizumab and Combination Chemotherapy in rectal cancer Until Surgery (BACCHUS): A phase II, multicentre, open-label, randomised study of neoadjuvant chemotherapy alone in patients with high-risk cancer of the rectum
title_short	Bevacizumab and Combination Chemotherapy in rectal cancer Until Surgery (BACCHUS): A phase II, multicentre, open-label, randomised study of neoadjuvant chemotherapy alone in patients with high-risk cancer of the rectum
title_full	Bevacizumab and Combination Chemotherapy in rectal cancer Until Surgery (BACCHUS): A phase II, multicentre, open-label, randomised study of neoadjuvant chemotherapy alone in patients with high-risk cancer of the rectum
title_fullStr	Bevacizumab and Combination Chemotherapy in rectal cancer Until Surgery (BACCHUS): A phase II, multicentre, open-label, randomised study of neoadjuvant chemotherapy alone in patients with high-risk cancer of the rectum
title_full_unstemmed	Bevacizumab and Combination Chemotherapy in rectal cancer Until Surgery (BACCHUS): A phase II, multicentre, open-label, randomised study of neoadjuvant chemotherapy alone in patients with high-risk cancer of the rectum
title_sort	bevacizumab and combination chemotherapy in rectal cancer until surgery (bacchus): a phase ii, multicentre, open-label, randomised study of neoadjuvant chemotherapy alone in patients with high-risk cancer of the rectum
publishDate	2020
url	https://scholarbank.nus.edu.sg/handle/10635/181427
_version_	1800914636922421248

Bevacizumab and Combination Chemotherapy in rectal cancer Until Surgery (BACCHUS): A phase II, multicentre, open-label, randomised study of neoadjuvant chemotherapy alone in patients with high-risk cancer of the rectum

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