Celecoxib increases miR-222 while deterring aromatase-expressing breast tumor growth in mice

Celecoxib increases miR-222 while deterring aromatase-expressing breast tumor growth in mice

10.1186/1471-2407-14-426

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Bibliographic Details
Main Authors:	Wong, T.Y, Li, F, Lin, S.-M, Chan, F.L, Chen, S, Leung, L.K
Other Authors:	DUKE-NUS MEDICAL SCHOOL
Format:	Article
Published:	2020
Subjects:	acetylsalicylic acid androstenedione aromatase celecoxib cyclin A cyclooxygenase 2 estradiol estrogen receptor alpha messenger RNA microRNA 222 Myc protein protein bcl xl transcription factor E2F2 cyclooxygenase 2 inhibitor microRNA MIRN222 microRNA, human pyrazole derivative sulfonamide animal experiment animal model animal tissue article body weight breast tumor controlled study down regulation estradiol blood level female liver weight MCF 7 cell line mouse nonhuman nude mouse protein expression tumor growth tumor xenograft anatomy and histology animal apoptosis blood cell cycle disease model drug effects drug screening gene expression regulation genetics human liver metabolism oncogene myc pathology tumor volume Animals Apoptosis Aromatase Aspirin Body Weight Breast Neoplasms Cell Cycle Cyclooxygenase 2 Cyclooxygenase 2 Inhibitors Disease Models, Animal E2F2 Transcription Factor Estradiol Estrogen Receptor alpha Female Gene Expression Regulation, Neoplastic Genes, myc Humans Liver MCF-7 Cells Mice MicroRNAs Pyrazoles RNA, Messenger Sulfonamides Tumor Burden Xenograft Model Antitumor Assays
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/181498
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Institution:	National University of Singapore

Description
Summary:	10.1186/1471-2407-14-426