Solomonsterol A, a marine pregnane-X-receptor agonist, attenuates inflammation and immune dysfunction in a mouse model of arthritis

10.3390/md12010036

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Main Authors:	Mencarelli, A, D'Amore, C, Renga, B, Cipriani, S, Carino, A, Sepe, V, Perissutti, E, D'Auria, M.V, Zampella, A, Distrutti, E, Fiorucci, S
Other Authors:	DUKE-NUS MEDICAL SCHOOL
Format:	Article
Published:	2020
Subjects:	C reactive protein cell nucleus receptor chemokine collagen antibody cytokine gamma interferon interleukin 10 interleukin 17 macrophage inflammatory protein 1alpha pregnane derivative pregnane X receptor RANTES solomonsterol A tumor necrosis factor alpha unclassified drug adaptive immunity animal experiment animal model antiinflammatory activity article controlled study histopathology immunopathology inflammation innate immunity lymph node male mouse nonhuman rheumatoid arthritis scoring system sponge (Porifera) Theonella swinhoei Animals Anti-Inflammatory Agents Arthritis, Rheumatoid C-Reactive Protein Cartilage Chemokine CCL3 Chemokine CCL5 Cholanes Collagen Type II Cytokines Hepatocytes Humans Immunologic Deficiency Syndromes Interferon-gamma Interleukin-17 Liver Lymph Nodes Mice, Inbred C57BL Mice, Transgenic Models, Molecular Molecular Conformation Porifera Receptors, Steroid Sulfuric Acid Esters Transcriptional Activation Tumor Necrosis Factor-alpha
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/181535
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Institution:	National University of Singapore

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spelling	sg-nus-scholar.10635-1815352023-11-01T07:43:02Z Solomonsterol A, a marine pregnane-X-receptor agonist, attenuates inflammation and immune dysfunction in a mouse model of arthritis Mencarelli, A D'Amore, C Renga, B Cipriani, S Carino, A Sepe, V Perissutti, E D'Auria, M.V Zampella, A Distrutti, E Fiorucci, S DUKE-NUS MEDICAL SCHOOL C reactive protein cell nucleus receptor chemokine collagen antibody cytokine gamma interferon interleukin 10 interleukin 17 macrophage inflammatory protein 1alpha pregnane derivative pregnane X receptor RANTES solomonsterol A tumor necrosis factor alpha unclassified drug adaptive immunity animal experiment animal model antiinflammatory activity article controlled study histopathology immunopathology inflammation innate immunity lymph node male mouse nonhuman rheumatoid arthritis scoring system sponge (Porifera) Theonella swinhoei Animals Anti-Inflammatory Agents Arthritis, Rheumatoid C-Reactive Protein Cartilage Chemokine CCL3 Chemokine CCL5 Cholanes Collagen Type II Cytokines Hepatocytes Humans Immunologic Deficiency Syndromes Interferon-gamma Interleukin-17 Liver Lymph Nodes Mice, Inbred C57BL Mice, Transgenic Models, Molecular Molecular Conformation Porifera Receptors, Steroid Sulfuric Acid Esters Transcriptional Activation Tumor Necrosis Factor-alpha 10.3390/md12010036 Marine Drugs 12 1 36-53 2020-10-27T11:13:47Z 2020-10-27T11:13:47Z 2014 Article Mencarelli, A, D'Amore, C, Renga, B, Cipriani, S, Carino, A, Sepe, V, Perissutti, E, D'Auria, M.V, Zampella, A, Distrutti, E, Fiorucci, S (2014). Solomonsterol A, a marine pregnane-X-receptor agonist, attenuates inflammation and immune dysfunction in a mouse model of arthritis. Marine Drugs 12 (1) : 36-53. ScholarBank@NUS Repository. https://doi.org/10.3390/md12010036 16603397 https://scholarbank.nus.edu.sg/handle/10635/181535 Attribution 4.0 International http://creativecommons.org/licenses/by/4.0/ Unpaywall 20201031
institution	National University of Singapore
building	NUS Library
continent	Asia
country	Singapore Singapore
content_provider	NUS Library
collection	ScholarBank@NUS
topic	C reactive protein cell nucleus receptor chemokine collagen antibody cytokine gamma interferon interleukin 10 interleukin 17 macrophage inflammatory protein 1alpha pregnane derivative pregnane X receptor RANTES solomonsterol A tumor necrosis factor alpha unclassified drug adaptive immunity animal experiment animal model antiinflammatory activity article controlled study histopathology immunopathology inflammation innate immunity lymph node male mouse nonhuman rheumatoid arthritis scoring system sponge (Porifera) Theonella swinhoei Animals Anti-Inflammatory Agents Arthritis, Rheumatoid C-Reactive Protein Cartilage Chemokine CCL3 Chemokine CCL5 Cholanes Collagen Type II Cytokines Hepatocytes Humans Immunologic Deficiency Syndromes Interferon-gamma Interleukin-17 Liver Lymph Nodes Mice, Inbred C57BL Mice, Transgenic Models, Molecular Molecular Conformation Porifera Receptors, Steroid Sulfuric Acid Esters Transcriptional Activation Tumor Necrosis Factor-alpha
spellingShingle	C reactive protein cell nucleus receptor chemokine collagen antibody cytokine gamma interferon interleukin 10 interleukin 17 macrophage inflammatory protein 1alpha pregnane derivative pregnane X receptor RANTES solomonsterol A tumor necrosis factor alpha unclassified drug adaptive immunity animal experiment animal model antiinflammatory activity article controlled study histopathology immunopathology inflammation innate immunity lymph node male mouse nonhuman rheumatoid arthritis scoring system sponge (Porifera) Theonella swinhoei Animals Anti-Inflammatory Agents Arthritis, Rheumatoid C-Reactive Protein Cartilage Chemokine CCL3 Chemokine CCL5 Cholanes Collagen Type II Cytokines Hepatocytes Humans Immunologic Deficiency Syndromes Interferon-gamma Interleukin-17 Liver Lymph Nodes Mice, Inbred C57BL Mice, Transgenic Models, Molecular Molecular Conformation Porifera Receptors, Steroid Sulfuric Acid Esters Transcriptional Activation Tumor Necrosis Factor-alpha Mencarelli, A D'Amore, C Renga, B Cipriani, S Carino, A Sepe, V Perissutti, E D'Auria, M.V Zampella, A Distrutti, E Fiorucci, S Solomonsterol A, a marine pregnane-X-receptor agonist, attenuates inflammation and immune dysfunction in a mouse model of arthritis
description	10.3390/md12010036
author2	DUKE-NUS MEDICAL SCHOOL
author_facet	DUKE-NUS MEDICAL SCHOOL Mencarelli, A D'Amore, C Renga, B Cipriani, S Carino, A Sepe, V Perissutti, E D'Auria, M.V Zampella, A Distrutti, E Fiorucci, S
format	Article
author	Mencarelli, A D'Amore, C Renga, B Cipriani, S Carino, A Sepe, V Perissutti, E D'Auria, M.V Zampella, A Distrutti, E Fiorucci, S
author_sort	Mencarelli, A
title	Solomonsterol A, a marine pregnane-X-receptor agonist, attenuates inflammation and immune dysfunction in a mouse model of arthritis
title_short	Solomonsterol A, a marine pregnane-X-receptor agonist, attenuates inflammation and immune dysfunction in a mouse model of arthritis
title_full	Solomonsterol A, a marine pregnane-X-receptor agonist, attenuates inflammation and immune dysfunction in a mouse model of arthritis
title_fullStr	Solomonsterol A, a marine pregnane-X-receptor agonist, attenuates inflammation and immune dysfunction in a mouse model of arthritis
title_full_unstemmed	Solomonsterol A, a marine pregnane-X-receptor agonist, attenuates inflammation and immune dysfunction in a mouse model of arthritis
title_sort	solomonsterol a, a marine pregnane-x-receptor agonist, attenuates inflammation and immune dysfunction in a mouse model of arthritis
publishDate	2020
url	https://scholarbank.nus.edu.sg/handle/10635/181535
_version_	1781792539634827264

Solomonsterol A, a marine pregnane-X-receptor agonist, attenuates inflammation and immune dysfunction in a mouse model of arthritis

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