A rheostat mechanism governs the bifurcation of carbon flux in mycobacteria
10.1038/ncomms12527
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sg-nus-scholar.10635-1824362024-03-27T08:18:16Z A rheostat mechanism governs the bifurcation of carbon flux in mycobacteria Murima, P Zimmermann, M Chopra, T Pojer, F Fonti, G Dal Peraro, M Alonso, S Sauer, U Pethe, K McKinney, J.D MICROBIOLOGY AND IMMUNOLOGY carbon glyoxylic acid isocitrate lyase bacterial protein carbon fatty acid glyoxylic acid derivative isocitrate dehydrogenase bifurcation carbon flux chemotherapy coliform bacterium enzyme activity fatty acid infectivity metabolism partitioning pathogenicity steady-state equilibrium tuberculosis allosterism Article bacterial growth bacterial strain biosynthesis carbon source citric acid cycle controlled study energy metabolism energy yield enzyme phosphorylation Escherichia coli fatty acid metabolism Mycobacterium tuberculosis nonhuman regulatory mechanism tuberculosis biological model carbon cycle classification kinetics metabolism Mycobacterium species difference Corynebacterineae Escherichia coli Mycobacterium tuberculosis Bacterial Proteins Carbon Carbon Cycle Citric Acid Cycle Fatty Acids Glyoxylates Isocitrate Dehydrogenase Isocitrate Lyase Kinetics Models, Biological Mycobacterium Species Specificity 10.1038/ncomms12527 Nature Communications 7 12527 2020-10-31T11:27:59Z 2020-10-31T11:27:59Z 2016 Article Murima, P, Zimmermann, M, Chopra, T, Pojer, F, Fonti, G, Dal Peraro, M, Alonso, S, Sauer, U, Pethe, K, McKinney, J.D (2016). A rheostat mechanism governs the bifurcation of carbon flux in mycobacteria. Nature Communications 7 : 12527. ScholarBank@NUS Repository. https://doi.org/10.1038/ncomms12527 2041-1723 https://scholarbank.nus.edu.sg/handle/10635/182436 Attribution 4.0 International http://creativecommons.org/licenses/by/4.0/ Nature Publishing Group Unpaywall 20201031 |
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carbon glyoxylic acid isocitrate lyase bacterial protein carbon fatty acid glyoxylic acid derivative isocitrate dehydrogenase bifurcation carbon flux chemotherapy coliform bacterium enzyme activity fatty acid infectivity metabolism partitioning pathogenicity steady-state equilibrium tuberculosis allosterism Article bacterial growth bacterial strain biosynthesis carbon source citric acid cycle controlled study energy metabolism energy yield enzyme phosphorylation Escherichia coli fatty acid metabolism Mycobacterium tuberculosis nonhuman regulatory mechanism tuberculosis biological model carbon cycle classification kinetics metabolism Mycobacterium species difference Corynebacterineae Escherichia coli Mycobacterium tuberculosis Bacterial Proteins Carbon Carbon Cycle Citric Acid Cycle Fatty Acids Glyoxylates Isocitrate Dehydrogenase Isocitrate Lyase Kinetics Models, Biological Mycobacterium Species Specificity |
| spellingShingle |
carbon glyoxylic acid isocitrate lyase bacterial protein carbon fatty acid glyoxylic acid derivative isocitrate dehydrogenase bifurcation carbon flux chemotherapy coliform bacterium enzyme activity fatty acid infectivity metabolism partitioning pathogenicity steady-state equilibrium tuberculosis allosterism Article bacterial growth bacterial strain biosynthesis carbon source citric acid cycle controlled study energy metabolism energy yield enzyme phosphorylation Escherichia coli fatty acid metabolism Mycobacterium tuberculosis nonhuman regulatory mechanism tuberculosis biological model carbon cycle classification kinetics metabolism Mycobacterium species difference Corynebacterineae Escherichia coli Mycobacterium tuberculosis Bacterial Proteins Carbon Carbon Cycle Citric Acid Cycle Fatty Acids Glyoxylates Isocitrate Dehydrogenase Isocitrate Lyase Kinetics Models, Biological Mycobacterium Species Specificity Murima, P Zimmermann, M Chopra, T Pojer, F Fonti, G Dal Peraro, M Alonso, S Sauer, U Pethe, K McKinney, J.D A rheostat mechanism governs the bifurcation of carbon flux in mycobacteria |
| description |
10.1038/ncomms12527 |
| author2 |
MICROBIOLOGY AND IMMUNOLOGY |
| author_facet |
MICROBIOLOGY AND IMMUNOLOGY Murima, P Zimmermann, M Chopra, T Pojer, F Fonti, G Dal Peraro, M Alonso, S Sauer, U Pethe, K McKinney, J.D |
| format |
Article |
| author |
Murima, P Zimmermann, M Chopra, T Pojer, F Fonti, G Dal Peraro, M Alonso, S Sauer, U Pethe, K McKinney, J.D |
| author_sort |
Murima, P |
| title |
A rheostat mechanism governs the bifurcation of carbon flux in mycobacteria |
| title_short |
A rheostat mechanism governs the bifurcation of carbon flux in mycobacteria |
| title_full |
A rheostat mechanism governs the bifurcation of carbon flux in mycobacteria |
| title_fullStr |
A rheostat mechanism governs the bifurcation of carbon flux in mycobacteria |
| title_full_unstemmed |
A rheostat mechanism governs the bifurcation of carbon flux in mycobacteria |
| title_sort |
rheostat mechanism governs the bifurcation of carbon flux in mycobacteria |
| publisher |
Nature Publishing Group |
| publishDate |
2020 |
| url |
https://scholarbank.nus.edu.sg/handle/10635/182436 |
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1795301339366948864 |