Deletion of Wiskott-Aldrich syndrome protein triggers Rac2 activity and increased cross-presentation by dendritic cells

Deletion of Wiskott-Aldrich syndrome protein triggers Rac2 activity and increased cross-presentation by dendritic cells

10.1038/ncomms12175

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التفاصيل البيبلوغرافية
المؤلفون الرئيسيون:	Baptista, M.A.P, Keszei, M, Oliveira, M, Sunahara, K.K.S, Andersson, J, Dahlberg, C.I.M, Worth, A.J, Liedén, A, Kuo, I.-C, Wallin, R.P.A, Snapper, S.B, Eidsmo, L, Scheynius, A, Karlsson, M.C.I, Bouma, G, Burns, S.O, Forsell, M.N.E, Thrasher, A.J, Nylén, S, Westerberg, L.S
مؤلفون آخرون:	PAEDIATRICS
التنسيق:	مقال
منشور في:	Nature Publishing Group 2020
الموضوعات:	gamma interferon Rac2 protein reactive oxygen metabolite Wiskott Aldrich syndrome protein arthropod protein Dermatophagoides pteronyssinus antigen p 2 house dust allergen Rac protein cells and cell components disease enzyme enzyme activity gene mutation pH protein animal cell animal experiment animal model animal tissue Article CD4+ T lymphocyte CD8+ T lymphocyte cell expansion controlled study cross presentation dendritic cell enzyme activation female gene deletion gene expression intracellular signaling lymphatic drainage male mouse nonhuman phagosome protein function spleen animal Bagg albino mouse C57BL mouse cell proliferation chemistry deficiency immunology knockout mouse Leishmania major lymphocyte count metabolism parasitology pathology physiology protein domain skin Mus Animals Antigens, Dermatophagoides Arthropod Proteins CD8-Positive T-Lymphocytes Cell Proliferation Cross-Priming Dendritic Cells Gene Deletion Interferon-gamma Lymphocyte Count Mice, Inbred BALB C Mice, Inbred C57BL Mice, Knockout Phagosomes Protein Domains rac GTP-Binding Proteins Reactive Oxygen Species Skin Wiskott-Aldrich Syndrome Protein
الوصول للمادة أونلاين:	https://scholarbank.nus.edu.sg/handle/10635/182446
الوسوم:	إضافة وسم لا توجد وسوم, كن أول من يضع وسما على هذه التسجيلة!

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الملخص:	10.1038/ncomms12175