Deletion of Wiskott-Aldrich syndrome protein triggers Rac2 activity and increased cross-presentation by dendritic cells

10.1038/ncomms12175

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Main Authors:	Baptista, M.A.P, Keszei, M, Oliveira, M, Sunahara, K.K.S, Andersson, J, Dahlberg, C.I.M, Worth, A.J, Liedén, A, Kuo, I.-C, Wallin, R.P.A, Snapper, S.B, Eidsmo, L, Scheynius, A, Karlsson, M.C.I, Bouma, G, Burns, S.O, Forsell, M.N.E, Thrasher, A.J, Nylén, S, Westerberg, L.S
Other Authors:	PAEDIATRICS
Format:	Article
Published:	Nature Publishing Group 2020
Subjects:	gamma interferon Rac2 protein reactive oxygen metabolite Wiskott Aldrich syndrome protein arthropod protein Dermatophagoides pteronyssinus antigen p 2 house dust allergen Rac protein cells and cell components disease enzyme enzyme activity gene mutation pH protein animal cell animal experiment animal model animal tissue Article CD4+ T lymphocyte CD8+ T lymphocyte cell expansion controlled study cross presentation dendritic cell enzyme activation female gene deletion gene expression intracellular signaling lymphatic drainage male mouse nonhuman phagosome protein function spleen animal Bagg albino mouse C57BL mouse cell proliferation chemistry deficiency immunology knockout mouse Leishmania major lymphocyte count metabolism parasitology pathology physiology protein domain skin Mus Animals Antigens, Dermatophagoides Arthropod Proteins CD8-Positive T-Lymphocytes Cell Proliferation Cross-Priming Dendritic Cells Gene Deletion Interferon-gamma Lymphocyte Count Mice, Inbred BALB C Mice, Inbred C57BL Mice, Knockout Phagosomes Protein Domains rac GTP-Binding Proteins Reactive Oxygen Species Skin Wiskott-Aldrich Syndrome Protein
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/182446
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Institution:	National University of Singapore

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spelling	sg-nus-scholar.10635-1824462024-11-14T21:26:03Z Deletion of Wiskott-Aldrich syndrome protein triggers Rac2 activity and increased cross-presentation by dendritic cells Baptista, M.A.P Keszei, M Oliveira, M Sunahara, K.K.S Andersson, J Dahlberg, C.I.M Worth, A.J Liedén, A Kuo, I.-C Wallin, R.P.A Snapper, S.B Eidsmo, L Scheynius, A Karlsson, M.C.I Bouma, G Burns, S.O Forsell, M.N.E Thrasher, A.J Nylén, S Westerberg, L.S PAEDIATRICS gamma interferon Rac2 protein reactive oxygen metabolite Wiskott Aldrich syndrome protein arthropod protein Dermatophagoides pteronyssinus antigen p 2 gamma interferon house dust allergen Rac protein Rac2 protein reactive oxygen metabolite Wiskott Aldrich syndrome protein cells and cell components disease enzyme enzyme activity gene mutation pH protein animal cell animal experiment animal model animal tissue Article CD4+ T lymphocyte CD8+ T lymphocyte cell expansion controlled study cross presentation dendritic cell enzyme activation enzyme activity female gene deletion gene expression intracellular signaling lymphatic drainage male mouse nonhuman pH phagosome protein function spleen animal Bagg albino mouse C57BL mouse cell proliferation chemistry cross presentation deficiency dendritic cell gene deletion immunology knockout mouse Leishmania major lymphocyte count metabolism parasitology pathology physiology protein domain skin Mus Animals Antigens, Dermatophagoides Arthropod Proteins CD8-Positive T-Lymphocytes Cell Proliferation Cross-Priming Dendritic Cells Gene Deletion Interferon-gamma Leishmania major Lymphocyte Count Mice, Inbred BALB C Mice, Inbred C57BL Mice, Knockout Phagosomes Protein Domains rac GTP-Binding Proteins Reactive Oxygen Species Skin Wiskott-Aldrich Syndrome Protein 10.1038/ncomms12175 Nature Communications 7 12175 2020-10-31T11:29:45Z 2020-10-31T11:29:45Z 2016 Article Baptista, M.A.P, Keszei, M, Oliveira, M, Sunahara, K.K.S, Andersson, J, Dahlberg, C.I.M, Worth, A.J, Liedén, A, Kuo, I.-C, Wallin, R.P.A, Snapper, S.B, Eidsmo, L, Scheynius, A, Karlsson, M.C.I, Bouma, G, Burns, S.O, Forsell, M.N.E, Thrasher, A.J, Nylén, S, Westerberg, L.S (2016). Deletion of Wiskott-Aldrich syndrome protein triggers Rac2 activity and increased cross-presentation by dendritic cells. Nature Communications 7 : 12175. ScholarBank@NUS Repository. https://doi.org/10.1038/ncomms12175 2041-1723 https://scholarbank.nus.edu.sg/handle/10635/182446 Attribution 4.0 International http://creativecommons.org/licenses/by/4.0/ Nature Publishing Group Unpaywall 20201031
institution	National University of Singapore
building	NUS Library
continent	Asia
country	Singapore Singapore
content_provider	NUS Library
collection	ScholarBank@NUS
topic	gamma interferon Rac2 protein reactive oxygen metabolite Wiskott Aldrich syndrome protein arthropod protein Dermatophagoides pteronyssinus antigen p 2 gamma interferon house dust allergen Rac protein Rac2 protein reactive oxygen metabolite Wiskott Aldrich syndrome protein cells and cell components disease enzyme enzyme activity gene mutation pH protein animal cell animal experiment animal model animal tissue Article CD4+ T lymphocyte CD8+ T lymphocyte cell expansion controlled study cross presentation dendritic cell enzyme activation enzyme activity female gene deletion gene expression intracellular signaling lymphatic drainage male mouse nonhuman pH phagosome protein function spleen animal Bagg albino mouse C57BL mouse cell proliferation chemistry cross presentation deficiency dendritic cell gene deletion immunology knockout mouse Leishmania major lymphocyte count metabolism parasitology pathology physiology protein domain skin Mus Animals Antigens, Dermatophagoides Arthropod Proteins CD8-Positive T-Lymphocytes Cell Proliferation Cross-Priming Dendritic Cells Gene Deletion Interferon-gamma Leishmania major Lymphocyte Count Mice, Inbred BALB C Mice, Inbred C57BL Mice, Knockout Phagosomes Protein Domains rac GTP-Binding Proteins Reactive Oxygen Species Skin Wiskott-Aldrich Syndrome Protein
spellingShingle	gamma interferon Rac2 protein reactive oxygen metabolite Wiskott Aldrich syndrome protein arthropod protein Dermatophagoides pteronyssinus antigen p 2 gamma interferon house dust allergen Rac protein Rac2 protein reactive oxygen metabolite Wiskott Aldrich syndrome protein cells and cell components disease enzyme enzyme activity gene mutation pH protein animal cell animal experiment animal model animal tissue Article CD4+ T lymphocyte CD8+ T lymphocyte cell expansion controlled study cross presentation dendritic cell enzyme activation enzyme activity female gene deletion gene expression intracellular signaling lymphatic drainage male mouse nonhuman pH phagosome protein function spleen animal Bagg albino mouse C57BL mouse cell proliferation chemistry cross presentation deficiency dendritic cell gene deletion immunology knockout mouse Leishmania major lymphocyte count metabolism parasitology pathology physiology protein domain skin Mus Animals Antigens, Dermatophagoides Arthropod Proteins CD8-Positive T-Lymphocytes Cell Proliferation Cross-Priming Dendritic Cells Gene Deletion Interferon-gamma Leishmania major Lymphocyte Count Mice, Inbred BALB C Mice, Inbred C57BL Mice, Knockout Phagosomes Protein Domains rac GTP-Binding Proteins Reactive Oxygen Species Skin Wiskott-Aldrich Syndrome Protein Baptista, M.A.P Keszei, M Oliveira, M Sunahara, K.K.S Andersson, J Dahlberg, C.I.M Worth, A.J Liedén, A Kuo, I.-C Wallin, R.P.A Snapper, S.B Eidsmo, L Scheynius, A Karlsson, M.C.I Bouma, G Burns, S.O Forsell, M.N.E Thrasher, A.J Nylén, S Westerberg, L.S Deletion of Wiskott-Aldrich syndrome protein triggers Rac2 activity and increased cross-presentation by dendritic cells
description	10.1038/ncomms12175
author2	PAEDIATRICS
author_facet	PAEDIATRICS Baptista, M.A.P Keszei, M Oliveira, M Sunahara, K.K.S Andersson, J Dahlberg, C.I.M Worth, A.J Liedén, A Kuo, I.-C Wallin, R.P.A Snapper, S.B Eidsmo, L Scheynius, A Karlsson, M.C.I Bouma, G Burns, S.O Forsell, M.N.E Thrasher, A.J Nylén, S Westerberg, L.S
format	Article
author	Baptista, M.A.P Keszei, M Oliveira, M Sunahara, K.K.S Andersson, J Dahlberg, C.I.M Worth, A.J Liedén, A Kuo, I.-C Wallin, R.P.A Snapper, S.B Eidsmo, L Scheynius, A Karlsson, M.C.I Bouma, G Burns, S.O Forsell, M.N.E Thrasher, A.J Nylén, S Westerberg, L.S
author_sort	Baptista, M.A.P
title	Deletion of Wiskott-Aldrich syndrome protein triggers Rac2 activity and increased cross-presentation by dendritic cells
title_short	Deletion of Wiskott-Aldrich syndrome protein triggers Rac2 activity and increased cross-presentation by dendritic cells
title_full	Deletion of Wiskott-Aldrich syndrome protein triggers Rac2 activity and increased cross-presentation by dendritic cells
title_fullStr	Deletion of Wiskott-Aldrich syndrome protein triggers Rac2 activity and increased cross-presentation by dendritic cells
title_full_unstemmed	Deletion of Wiskott-Aldrich syndrome protein triggers Rac2 activity and increased cross-presentation by dendritic cells
title_sort	deletion of wiskott-aldrich syndrome protein triggers rac2 activity and increased cross-presentation by dendritic cells
publisher	Nature Publishing Group
publishDate	2020
url	https://scholarbank.nus.edu.sg/handle/10635/182446
_version_	1821183304221589504

Deletion of Wiskott-Aldrich syndrome protein triggers Rac2 activity and increased cross-presentation by dendritic cells

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