Female chromosome X mosaicism is age-related and preferentially affects the inactivated X chromosome

• Main Authors: MacHiela, M.J, Zhou, W, Karlins, E
• Other Authors: DUKE-NUS MEDICAL SCHOOL
• Format: Article
• Published: Nature Publishing Group 2020
• Subjects: age; bioassay; cancer; chromosome; cytogenetics; genetic analysis; genome; health risk; womens health; adult; aged; aging; Article; autosome mosaicism; centromere; controlled study; DNA methylation; female; genome-wide association study; groups by age; human; male; microarray analysis; polymerase chain reaction; sex chromosome mosaicism; sex difference; single nucleotide polymorphism; telomere; X chromosome inactivation; genetics; mosaicism; reproducibility; X chromosome; Aging; Chromosomes, Human, X; DNA Methylation; Female; Humans; Male; Mosaicism; Polymerase Chain Reaction; Reproducibility of Results; X Chromosome Inactivation
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/182461
• Institution: National University of Singapore

10.1038/ncomms11843