Cops2 promotes pluripotency maintenance by Stabilizing Nanog Protein and Repressing Transcription

• Main Authors: Zhang, W, Ni, P, Mou, C, Zhang, Y, Guo, H, Zhao, T, Loh, Y.-H, Chen, L
• Other Authors: BIOLOGICAL SCIENCES
• Format: Article
• Published: Nature Publishing Group 2020
• Subjects: COP9 signalosome; Cops2 protein, mouse; Nanog protein, mouse; nuclear protein; octamer transcription factor 4; Pou5f1 protein, mouse; small interfering RNA; Sox4 protein, mouse; transcription factor; transcription factor NANOG; transcription factor Sox; amino acid sequence; animal; antagonists and inhibitors; cell reprogramming technique; cell self-renewal; cytology; embryoid body; embryonic stem cell; gene expression regulation; gene knockdown; genetic transcription; genetics; metabolism; mouse; physiology; protein degradation; protein stability; RNA interference; sheep; Amino Acid Sequence; Animals; Cell Self Renewal; Cellular Reprogramming Techniques; COP9 Signalosome Complex; Embryoid Bodies; Embryonic Stem Cells; Gene Expression Regulation, Developmental; Gene Knockdown Techniques; Mice; Nanog Homeobox Protein; Nuclear Proteins; Octamer Transcription Factor-3; Protein Stability; Proteolysis; RNA Interference; RNA, Small Interfering; Sheep; SOXC Transcription Factors; Transcription Factors; Transcription, Genetic
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/182468
• Institution: National University of Singapore

10.1038/srep26804