ITF2357 transactivates Id3 and regulate TGF?/BMP7 signaling pathways to attenuate corneal fibrosis
10.1038/srep20841
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2020
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sg-nus-scholar.10635-1825052024-11-11T02:02:49Z ITF2357 transactivates Id3 and regulate TGF?/BMP7 signaling pathways to attenuate corneal fibrosis Lim, R.R Tan, A Liu, Y.-C Barathi, V.A Mohan, R.R Mehta, J.S Chaurasia, S.S DUKE-NUS MEDICAL SCHOOL OPHTHALMOLOGY collagen type 1 collagen type 4 fibronectin givinostat hydrochloride histone deacetylase inhibitor hydroxamic acid inhibitor of differentiation protein osteogenic protein 1 procollagen proline 2 oxoglutarate 4 dioxygenase Smad protein transforming growth factor beta vitronectin receptor adverse effects animal antagonists and inhibitors cornea stroma disease model drug effects fibroblast fibrosis gene expression regulation genetics human metabolism pathology phosphorylation photorefractive keratectomy primary cell culture rabbits and hares signal transduction Animals Bone Morphogenetic Protein 7 Collagen Type I Collagen Type IV Corneal Stroma Disease Models, Animal Fibroblasts Fibronectins Fibrosis Gene Expression Regulation Histone Deacetylase Inhibitors Humans Hydroxamic Acids Inhibitor of Differentiation Proteins Integrin alphaVbeta3 Phosphorylation Photorefractive Keratectomy Primary Cell Culture Procollagen-Proline Dioxygenase Rabbits Signal Transduction Smad Proteins Transforming Growth Factor beta 10.1038/srep20841 Scientific Reports 6 20841 2020-10-31T11:41:30Z 2020-10-31T11:41:30Z 2016 Article Lim, R.R, Tan, A, Liu, Y.-C, Barathi, V.A, Mohan, R.R, Mehta, J.S, Chaurasia, S.S (2016). ITF2357 transactivates Id3 and regulate TGF?/BMP7 signaling pathways to attenuate corneal fibrosis. Scientific Reports 6 : 20841. ScholarBank@NUS Repository. https://doi.org/10.1038/srep20841 2045-2322 https://scholarbank.nus.edu.sg/handle/10635/182505 Attribution 4.0 International http://creativecommons.org/licenses/by/4.0/ Nature Publishing Group Unpaywall 20201031 |
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collagen type 1 collagen type 4 fibronectin givinostat hydrochloride histone deacetylase inhibitor hydroxamic acid inhibitor of differentiation protein osteogenic protein 1 procollagen proline 2 oxoglutarate 4 dioxygenase Smad protein transforming growth factor beta vitronectin receptor adverse effects animal antagonists and inhibitors cornea stroma disease model drug effects fibroblast fibrosis gene expression regulation genetics human metabolism pathology phosphorylation photorefractive keratectomy primary cell culture rabbits and hares signal transduction Animals Bone Morphogenetic Protein 7 Collagen Type I Collagen Type IV Corneal Stroma Disease Models, Animal Fibroblasts Fibronectins Fibrosis Gene Expression Regulation Histone Deacetylase Inhibitors Humans Hydroxamic Acids Inhibitor of Differentiation Proteins Integrin alphaVbeta3 Phosphorylation Photorefractive Keratectomy Primary Cell Culture Procollagen-Proline Dioxygenase Rabbits Signal Transduction Smad Proteins Transforming Growth Factor beta |
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collagen type 1 collagen type 4 fibronectin givinostat hydrochloride histone deacetylase inhibitor hydroxamic acid inhibitor of differentiation protein osteogenic protein 1 procollagen proline 2 oxoglutarate 4 dioxygenase Smad protein transforming growth factor beta vitronectin receptor adverse effects animal antagonists and inhibitors cornea stroma disease model drug effects fibroblast fibrosis gene expression regulation genetics human metabolism pathology phosphorylation photorefractive keratectomy primary cell culture rabbits and hares signal transduction Animals Bone Morphogenetic Protein 7 Collagen Type I Collagen Type IV Corneal Stroma Disease Models, Animal Fibroblasts Fibronectins Fibrosis Gene Expression Regulation Histone Deacetylase Inhibitors Humans Hydroxamic Acids Inhibitor of Differentiation Proteins Integrin alphaVbeta3 Phosphorylation Photorefractive Keratectomy Primary Cell Culture Procollagen-Proline Dioxygenase Rabbits Signal Transduction Smad Proteins Transforming Growth Factor beta Lim, R.R Tan, A Liu, Y.-C Barathi, V.A Mohan, R.R Mehta, J.S Chaurasia, S.S ITF2357 transactivates Id3 and regulate TGF?/BMP7 signaling pathways to attenuate corneal fibrosis |
| description |
10.1038/srep20841 |
| author2 |
DUKE-NUS MEDICAL SCHOOL |
| author_facet |
DUKE-NUS MEDICAL SCHOOL Lim, R.R Tan, A Liu, Y.-C Barathi, V.A Mohan, R.R Mehta, J.S Chaurasia, S.S |
| format |
Article |
| author |
Lim, R.R Tan, A Liu, Y.-C Barathi, V.A Mohan, R.R Mehta, J.S Chaurasia, S.S |
| author_sort |
Lim, R.R |
| title |
ITF2357 transactivates Id3 and regulate TGF?/BMP7 signaling pathways to attenuate corneal fibrosis |
| title_short |
ITF2357 transactivates Id3 and regulate TGF?/BMP7 signaling pathways to attenuate corneal fibrosis |
| title_full |
ITF2357 transactivates Id3 and regulate TGF?/BMP7 signaling pathways to attenuate corneal fibrosis |
| title_fullStr |
ITF2357 transactivates Id3 and regulate TGF?/BMP7 signaling pathways to attenuate corneal fibrosis |
| title_full_unstemmed |
ITF2357 transactivates Id3 and regulate TGF?/BMP7 signaling pathways to attenuate corneal fibrosis |
| title_sort |
itf2357 transactivates id3 and regulate tgf?/bmp7 signaling pathways to attenuate corneal fibrosis |
| publisher |
Nature Publishing Group |
| publishDate |
2020 |
| url |
https://scholarbank.nus.edu.sg/handle/10635/182505 |
| _version_ |
1821206191702802432 |