The KDM3A-KLF2-IRF4 axis maintains myeloma cell survival

10.1038/ncomms10258

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Main Authors:	Ohguchi, H, Hideshima, T, Bhasin, M.K, Gorgun, G.T, Santo, L, Cea, M, Samur, M.K, Mimura, N, Suzuki, R, Tai, Y.-T, Carrasco, R.D, Raje, N, Richardson, P.G, Munshi, N.C, Harigae, H, Sanda, T, Sakai, J, Anderson, K.C
Other Authors:	MEDICINE
Format:	Article
Published:	Nature Publishing Group 2020
Subjects:	caspase 7 caspase 8 histone demethylase histone H3 interferon regulatory factor 4 kruppel like factor 2 nicotinamide adenine dinucleotide adenosine diphosphate ribosyltransferase protein KDM3A unclassified drug histone interferon regulatory factor interferon regulatory factor-4 KDM3A protein, human KLF2 protein, human kruppel like factor anatomy apoptosis bone cells and cell components gene expression tumor animal cell animal experiment animal model animal tissue Article autoregulation bone marrow bone marrow stroma cell cell adhesion cell homing cell interaction cell survival controlled study gene silencing histone demethylation human human cell immunoblotting in vitro study in vivo study male microarray analysis monoclonal immunoglobulinemia mouse multiple myeloma myeloma cell nonhuman transactivation upregulation cell motion gene expression regulation genetics metabolism physiology tumor cell line Cell Adhesion Cell Line, Tumor Cell Movement Gene Expression Regulation, Neoplastic Gene Knockdown Techniques Histones Humans Interferon Regulatory Factors Jumonji Domain-Containing Histone Demethylases Kruppel-Like Transcription Factors Multiple Myeloma
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/182516
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Institution:	National University of Singapore

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spelling	sg-nus-scholar.10635-1825162024-05-08T09:52:09Z The KDM3A-KLF2-IRF4 axis maintains myeloma cell survival Ohguchi, H Hideshima, T Bhasin, M.K Gorgun, G.T Santo, L Cea, M Samur, M.K Mimura, N Suzuki, R Tai, Y.-T Carrasco, R.D Raje, N Richardson, P.G Munshi, N.C Harigae, H Sanda, T Sakai, J Anderson, K.C MEDICINE caspase 7 caspase 8 histone demethylase histone H3 interferon regulatory factor 4 kruppel like factor 2 nicotinamide adenine dinucleotide adenosine diphosphate ribosyltransferase protein KDM3A unclassified drug histone histone demethylase interferon regulatory factor interferon regulatory factor-4 KDM3A protein, human KLF2 protein, human kruppel like factor anatomy apoptosis bone cells and cell components gene expression tumor animal cell animal experiment animal model animal tissue apoptosis Article autoregulation bone marrow bone marrow stroma cell cell adhesion cell homing cell interaction cell survival controlled study gene silencing histone demethylation human human cell immunoblotting in vitro study in vivo study male microarray analysis monoclonal immunoglobulinemia mouse multiple myeloma myeloma cell nonhuman transactivation upregulation cell motion gene expression regulation genetics metabolism physiology tumor cell line Cell Adhesion Cell Line, Tumor Cell Movement Gene Expression Regulation, Neoplastic Gene Knockdown Techniques Histones Humans Interferon Regulatory Factors Jumonji Domain-Containing Histone Demethylases Kruppel-Like Transcription Factors Multiple Myeloma 10.1038/ncomms10258 Nature Communications 7 10258 2020-10-31T11:43:33Z 2020-10-31T11:43:33Z 2016 Article Ohguchi, H, Hideshima, T, Bhasin, M.K, Gorgun, G.T, Santo, L, Cea, M, Samur, M.K, Mimura, N, Suzuki, R, Tai, Y.-T, Carrasco, R.D, Raje, N, Richardson, P.G, Munshi, N.C, Harigae, H, Sanda, T, Sakai, J, Anderson, K.C (2016). The KDM3A-KLF2-IRF4 axis maintains myeloma cell survival. Nature Communications 7 : 10258. ScholarBank@NUS Repository. https://doi.org/10.1038/ncomms10258 2041-1723 https://scholarbank.nus.edu.sg/handle/10635/182516 Attribution 4.0 International http://creativecommons.org/licenses/by/4.0/ Nature Publishing Group Unpaywall 20201031
institution	National University of Singapore
building	NUS Library
continent	Asia
country	Singapore Singapore
content_provider	NUS Library
collection	ScholarBank@NUS
topic	caspase 7 caspase 8 histone demethylase histone H3 interferon regulatory factor 4 kruppel like factor 2 nicotinamide adenine dinucleotide adenosine diphosphate ribosyltransferase protein KDM3A unclassified drug histone histone demethylase interferon regulatory factor interferon regulatory factor-4 KDM3A protein, human KLF2 protein, human kruppel like factor anatomy apoptosis bone cells and cell components gene expression tumor animal cell animal experiment animal model animal tissue apoptosis Article autoregulation bone marrow bone marrow stroma cell cell adhesion cell homing cell interaction cell survival controlled study gene silencing histone demethylation human human cell immunoblotting in vitro study in vivo study male microarray analysis monoclonal immunoglobulinemia mouse multiple myeloma myeloma cell nonhuman transactivation upregulation cell motion gene expression regulation genetics metabolism physiology tumor cell line Cell Adhesion Cell Line, Tumor Cell Movement Gene Expression Regulation, Neoplastic Gene Knockdown Techniques Histones Humans Interferon Regulatory Factors Jumonji Domain-Containing Histone Demethylases Kruppel-Like Transcription Factors Multiple Myeloma
spellingShingle	caspase 7 caspase 8 histone demethylase histone H3 interferon regulatory factor 4 kruppel like factor 2 nicotinamide adenine dinucleotide adenosine diphosphate ribosyltransferase protein KDM3A unclassified drug histone histone demethylase interferon regulatory factor interferon regulatory factor-4 KDM3A protein, human KLF2 protein, human kruppel like factor anatomy apoptosis bone cells and cell components gene expression tumor animal cell animal experiment animal model animal tissue apoptosis Article autoregulation bone marrow bone marrow stroma cell cell adhesion cell homing cell interaction cell survival controlled study gene silencing histone demethylation human human cell immunoblotting in vitro study in vivo study male microarray analysis monoclonal immunoglobulinemia mouse multiple myeloma myeloma cell nonhuman transactivation upregulation cell motion gene expression regulation genetics metabolism physiology tumor cell line Cell Adhesion Cell Line, Tumor Cell Movement Gene Expression Regulation, Neoplastic Gene Knockdown Techniques Histones Humans Interferon Regulatory Factors Jumonji Domain-Containing Histone Demethylases Kruppel-Like Transcription Factors Multiple Myeloma Ohguchi, H Hideshima, T Bhasin, M.K Gorgun, G.T Santo, L Cea, M Samur, M.K Mimura, N Suzuki, R Tai, Y.-T Carrasco, R.D Raje, N Richardson, P.G Munshi, N.C Harigae, H Sanda, T Sakai, J Anderson, K.C The KDM3A-KLF2-IRF4 axis maintains myeloma cell survival
description	10.1038/ncomms10258
author2	MEDICINE
author_facet	MEDICINE Ohguchi, H Hideshima, T Bhasin, M.K Gorgun, G.T Santo, L Cea, M Samur, M.K Mimura, N Suzuki, R Tai, Y.-T Carrasco, R.D Raje, N Richardson, P.G Munshi, N.C Harigae, H Sanda, T Sakai, J Anderson, K.C
format	Article
author	Ohguchi, H Hideshima, T Bhasin, M.K Gorgun, G.T Santo, L Cea, M Samur, M.K Mimura, N Suzuki, R Tai, Y.-T Carrasco, R.D Raje, N Richardson, P.G Munshi, N.C Harigae, H Sanda, T Sakai, J Anderson, K.C
author_sort	Ohguchi, H
title	The KDM3A-KLF2-IRF4 axis maintains myeloma cell survival
title_short	The KDM3A-KLF2-IRF4 axis maintains myeloma cell survival
title_full	The KDM3A-KLF2-IRF4 axis maintains myeloma cell survival
title_fullStr	The KDM3A-KLF2-IRF4 axis maintains myeloma cell survival
title_full_unstemmed	The KDM3A-KLF2-IRF4 axis maintains myeloma cell survival
title_sort	kdm3a-klf2-irf4 axis maintains myeloma cell survival
publisher	Nature Publishing Group
publishDate	2020
url	https://scholarbank.nus.edu.sg/handle/10635/182516
_version_	1800914675484852224

The KDM3A-KLF2-IRF4 axis maintains myeloma cell survival

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