Collagen Sponge Functionalized with Chimeric Anti-BMP-2 Monoclonal Antibody Mediates Repair of Critical-Size Mandibular Continuity Defects in a Nonhuman Primate Model

• Main Authors: Xie, Y, Su, Y, Min, S, Tang, J, Goh, B.T, Saigo, L, Ansari, S, Moshaverinia, A, Zhang, C, Wang, J, Liu, Y, Khojasteh, A, Zadeh, H.H, Wang, S
• Other Authors: DUKE-NUS MEDICAL SCHOOL
• Format: Article
• Published: Hindawi 2020
• Subjects: biomaterial; bone morphogenetic protein 2; collagen sponge; monoclonal antibody; collagen; animal experiment; animal model; animal tissue; Article; bone density; bone mass; computed tomography scanner; cone beam computed tomography; controlled study; endotracheal tube; image reconstruction; mandible; nonhuman; ossification; osteotomy; polyglactin suture; primate; suture; tissue engineering; tissue scaffold; animal; bone development; bone regeneration; disease model; drug effects; genetics; growth, development and aging; human; immunology; Macaca fascicularis; Mandibular Diseases; pathology; pathophysiology; wound healing; Animals; Antibodies, Monoclonal; Bone Morphogenetic Protein 2; Bone Regeneration; Collagen; Disease Models, Animal; Humans; Mandible; Osteogenesis; Tissue Engineering; Tissue Scaffolds; Wound Healing
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/183574
• Institution: National University of Singapore

10.1155/2017/8094152