Differential effect of meclizine on the activity of human pregnane X receptor and constitutive androstane receptor

10.1124/jpet.110.175927

Saved in:

Bibliographic Details
Main Authors:	Lau, A.J, Yang, G, Rajaraman, G, Baucom, C.C, Chang, T.K.H
Other Authors:	PHARMACY
Format:	Article
Published:	American Society for Pharmacology and Experimental Therapeutics 2020
Subjects:	constitutive androstane receptor cytochrome P450 3A4 meclozine pregnane X receptor rifampicin steroid receptor coactivator 1 animal experiment article assay cell based reporter gene assay cell strain HepG2 controlled study drug antagonism drug effect drug receptor binding fluorescence resonance energy transfer gene expression genetic transfection human human cell ligand binding liver cell nonhuman nucleotide sequence priority journal rat Cells, Cultured Dose-Response Relationship, Drug Hep G2 Cells Hepatocytes Humans Meclizine Protein Binding Receptors, Cytoplasmic and Nuclear Receptors, Steroid
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/183913
Tags:	Add Tag No Tags, Be the first to tag this record!
Institution:	National University of Singapore

id	sg-nus-scholar.10635-183913
record_format	dspace
spelling	sg-nus-scholar.10635-1839132024-04-05T09:02:20Z Differential effect of meclizine on the activity of human pregnane X receptor and constitutive androstane receptor Lau, A.J Yang, G Rajaraman, G Baucom, C.C Chang, T.K.H PHARMACY constitutive androstane receptor cytochrome P450 3A4 meclozine pregnane X receptor rifampicin steroid receptor coactivator 1 animal experiment article assay cell based reporter gene assay cell strain HepG2 controlled study drug antagonism drug effect drug receptor binding fluorescence resonance energy transfer gene expression genetic transfection human human cell ligand binding liver cell nonhuman nucleotide sequence priority journal rat Cells, Cultured Dose-Response Relationship, Drug Hep G2 Cells Hepatocytes Humans Meclizine Protein Binding Receptors, Cytoplasmic and Nuclear Receptors, Steroid 10.1124/jpet.110.175927 Journal of Pharmacology and Experimental Therapeutics 336 3 816-826 2020-11-23T09:00:27Z 2020-11-23T09:00:27Z 2011 Article Lau, A.J, Yang, G, Rajaraman, G, Baucom, C.C, Chang, T.K.H (2011). Differential effect of meclizine on the activity of human pregnane X receptor and constitutive androstane receptor. Journal of Pharmacology and Experimental Therapeutics 336 (3) : 816-826. ScholarBank@NUS Repository. https://doi.org/10.1124/jpet.110.175927 0022-3565 https://scholarbank.nus.edu.sg/handle/10635/183913 Attribution 4.0 International http://creativecommons.org/licenses/by/4.0/ American Society for Pharmacology and Experimental Therapeutics Unpaywall 20201031
institution	National University of Singapore
building	NUS Library
continent	Asia
country	Singapore Singapore
content_provider	NUS Library
collection	ScholarBank@NUS
topic	constitutive androstane receptor cytochrome P450 3A4 meclozine pregnane X receptor rifampicin steroid receptor coactivator 1 animal experiment article assay cell based reporter gene assay cell strain HepG2 controlled study drug antagonism drug effect drug receptor binding fluorescence resonance energy transfer gene expression genetic transfection human human cell ligand binding liver cell nonhuman nucleotide sequence priority journal rat Cells, Cultured Dose-Response Relationship, Drug Hep G2 Cells Hepatocytes Humans Meclizine Protein Binding Receptors, Cytoplasmic and Nuclear Receptors, Steroid
spellingShingle	constitutive androstane receptor cytochrome P450 3A4 meclozine pregnane X receptor rifampicin steroid receptor coactivator 1 animal experiment article assay cell based reporter gene assay cell strain HepG2 controlled study drug antagonism drug effect drug receptor binding fluorescence resonance energy transfer gene expression genetic transfection human human cell ligand binding liver cell nonhuman nucleotide sequence priority journal rat Cells, Cultured Dose-Response Relationship, Drug Hep G2 Cells Hepatocytes Humans Meclizine Protein Binding Receptors, Cytoplasmic and Nuclear Receptors, Steroid Lau, A.J Yang, G Rajaraman, G Baucom, C.C Chang, T.K.H Differential effect of meclizine on the activity of human pregnane X receptor and constitutive androstane receptor
description	10.1124/jpet.110.175927
author2	PHARMACY
author_facet	PHARMACY Lau, A.J Yang, G Rajaraman, G Baucom, C.C Chang, T.K.H
format	Article
author	Lau, A.J Yang, G Rajaraman, G Baucom, C.C Chang, T.K.H
author_sort	Lau, A.J
title	Differential effect of meclizine on the activity of human pregnane X receptor and constitutive androstane receptor
title_short	Differential effect of meclizine on the activity of human pregnane X receptor and constitutive androstane receptor
title_full	Differential effect of meclizine on the activity of human pregnane X receptor and constitutive androstane receptor
title_fullStr	Differential effect of meclizine on the activity of human pregnane X receptor and constitutive androstane receptor
title_full_unstemmed	Differential effect of meclizine on the activity of human pregnane X receptor and constitutive androstane receptor
title_sort	differential effect of meclizine on the activity of human pregnane x receptor and constitutive androstane receptor
publisher	American Society for Pharmacology and Experimental Therapeutics
publishDate	2020
url	https://scholarbank.nus.edu.sg/handle/10635/183913
_version_	1800914732761219072

Differential effect of meclizine on the activity of human pregnane X receptor and constitutive androstane receptor

Similar Items