Interconnecting molecular pathways in the pathogenesis and drug sensitivity of T-cell acute lymphoblastic leukemia

10.1182/blood-2009-07-235143

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Main Authors:	Sanda, T, Li, X, Gutierrez, A, Ahn, Y, Neuberg, D.S, O'Neil, J, Strack, P.R, Winter, C.G, Winter, S.S, Larson, R.S, Von Boehmer, H, Look, A.T
Other Authors:	MEDICINE
Format:	Article
Published:	American Society of Hematology 2020
Subjects:	alvespimycin chaperone gamma secretase inhibitor heat shock protein 90 heat shock protein 90 inhibitor histone deacetylase immunoglobulin enhancer binding protein Myc protein Notch1 receptor phosphatidylinositol 3 kinase proteasome inhibitor protein kinase B tumor suppressor protein unclassified drug enzyme inhibitor NOTCH1 protein, human Notch1 protein, mouse secretase acute lymphoblastic leukemia algorithm analysis animal cell animal model article cancer growth cancer inhibition cell growth cell survival comparative study controlled study down regulation drug sensitivity female gene gene expression human human cell in vitro study leukemia cell leukemogenesis mouse nonhuman nucleotide sequence pathogenesis prediction priority journal signal transduction T lymphocyte animal cell cycle cell proliferation cell transformation drug antagonism experimental leukemia gene expression profiling genetics metabolism oncogene myc species difference tumor cell line Amyloid Precursor Protein Secretases Animals Cell Cycle Cell Line, Tumor Cell Proliferation Cell Survival Cell Transformation, Neoplastic Down-Regulation Enzyme Inhibitors Gene Expression Profiling Genes, myc Humans Leukemia, Experimental Mice Precursor T-Cell Lymphoblastic Leukemia-Lymphoma Receptor, Notch1 Signal Transduction Species Specificity
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/183915
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Institution:	National University of Singapore

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spelling	sg-nus-scholar.10635-1839152024-05-08T09:51:22Z Interconnecting molecular pathways in the pathogenesis and drug sensitivity of T-cell acute lymphoblastic leukemia Sanda, T Li, X Gutierrez, A Ahn, Y Neuberg, D.S O'Neil, J Strack, P.R Winter, C.G Winter, S.S Larson, R.S Von Boehmer, H Look, A.T MEDICINE alvespimycin chaperone gamma secretase inhibitor heat shock protein 90 heat shock protein 90 inhibitor histone deacetylase immunoglobulin enhancer binding protein Myc protein Notch1 receptor phosphatidylinositol 3 kinase proteasome inhibitor protein kinase B tumor suppressor protein unclassified drug enzyme inhibitor NOTCH1 protein, human Notch1 protein, mouse secretase acute lymphoblastic leukemia algorithm analysis animal cell animal model article cancer growth cancer inhibition cell growth cell survival comparative study controlled study down regulation drug sensitivity female gene gene expression human human cell in vitro study leukemia cell leukemogenesis mouse nonhuman nucleotide sequence pathogenesis prediction priority journal signal transduction T lymphocyte acute lymphoblastic leukemia animal cell cycle cell proliferation cell transformation drug antagonism experimental leukemia gene expression profiling genetics metabolism oncogene myc species difference tumor cell line Amyloid Precursor Protein Secretases Animals Cell Cycle Cell Line, Tumor Cell Proliferation Cell Survival Cell Transformation, Neoplastic Down-Regulation Enzyme Inhibitors Gene Expression Profiling Genes, myc Humans Leukemia, Experimental Mice Precursor T-Cell Lymphoblastic Leukemia-Lymphoma Receptor, Notch1 Signal Transduction Species Specificity 10.1182/blood-2009-07-235143 Blood 115 9 1735-1745 2020-11-23T09:00:51Z 2020-11-23T09:00:51Z 2010 Article Sanda, T, Li, X, Gutierrez, A, Ahn, Y, Neuberg, D.S, O'Neil, J, Strack, P.R, Winter, C.G, Winter, S.S, Larson, R.S, Von Boehmer, H, Look, A.T (2010). Interconnecting molecular pathways in the pathogenesis and drug sensitivity of T-cell acute lymphoblastic leukemia. Blood 115 (9) : 1735-1745. ScholarBank@NUS Repository. https://doi.org/10.1182/blood-2009-07-235143 0006-4971 https://scholarbank.nus.edu.sg/handle/10635/183915 Attribution 4.0 International http://creativecommons.org/licenses/by/4.0/ American Society of Hematology Unpaywall 20201031
institution	National University of Singapore
building	NUS Library
continent	Asia
country	Singapore Singapore
content_provider	NUS Library
collection	ScholarBank@NUS
topic	alvespimycin chaperone gamma secretase inhibitor heat shock protein 90 heat shock protein 90 inhibitor histone deacetylase immunoglobulin enhancer binding protein Myc protein Notch1 receptor phosphatidylinositol 3 kinase proteasome inhibitor protein kinase B tumor suppressor protein unclassified drug enzyme inhibitor NOTCH1 protein, human Notch1 protein, mouse secretase acute lymphoblastic leukemia algorithm analysis animal cell animal model article cancer growth cancer inhibition cell growth cell survival comparative study controlled study down regulation drug sensitivity female gene gene expression human human cell in vitro study leukemia cell leukemogenesis mouse nonhuman nucleotide sequence pathogenesis prediction priority journal signal transduction T lymphocyte acute lymphoblastic leukemia animal cell cycle cell proliferation cell transformation drug antagonism experimental leukemia gene expression profiling genetics metabolism oncogene myc species difference tumor cell line Amyloid Precursor Protein Secretases Animals Cell Cycle Cell Line, Tumor Cell Proliferation Cell Survival Cell Transformation, Neoplastic Down-Regulation Enzyme Inhibitors Gene Expression Profiling Genes, myc Humans Leukemia, Experimental Mice Precursor T-Cell Lymphoblastic Leukemia-Lymphoma Receptor, Notch1 Signal Transduction Species Specificity
spellingShingle	alvespimycin chaperone gamma secretase inhibitor heat shock protein 90 heat shock protein 90 inhibitor histone deacetylase immunoglobulin enhancer binding protein Myc protein Notch1 receptor phosphatidylinositol 3 kinase proteasome inhibitor protein kinase B tumor suppressor protein unclassified drug enzyme inhibitor NOTCH1 protein, human Notch1 protein, mouse secretase acute lymphoblastic leukemia algorithm analysis animal cell animal model article cancer growth cancer inhibition cell growth cell survival comparative study controlled study down regulation drug sensitivity female gene gene expression human human cell in vitro study leukemia cell leukemogenesis mouse nonhuman nucleotide sequence pathogenesis prediction priority journal signal transduction T lymphocyte acute lymphoblastic leukemia animal cell cycle cell proliferation cell transformation drug antagonism experimental leukemia gene expression profiling genetics metabolism oncogene myc species difference tumor cell line Amyloid Precursor Protein Secretases Animals Cell Cycle Cell Line, Tumor Cell Proliferation Cell Survival Cell Transformation, Neoplastic Down-Regulation Enzyme Inhibitors Gene Expression Profiling Genes, myc Humans Leukemia, Experimental Mice Precursor T-Cell Lymphoblastic Leukemia-Lymphoma Receptor, Notch1 Signal Transduction Species Specificity Sanda, T Li, X Gutierrez, A Ahn, Y Neuberg, D.S O'Neil, J Strack, P.R Winter, C.G Winter, S.S Larson, R.S Von Boehmer, H Look, A.T Interconnecting molecular pathways in the pathogenesis and drug sensitivity of T-cell acute lymphoblastic leukemia
description	10.1182/blood-2009-07-235143
author2	MEDICINE
author_facet	MEDICINE Sanda, T Li, X Gutierrez, A Ahn, Y Neuberg, D.S O'Neil, J Strack, P.R Winter, C.G Winter, S.S Larson, R.S Von Boehmer, H Look, A.T
format	Article
author	Sanda, T Li, X Gutierrez, A Ahn, Y Neuberg, D.S O'Neil, J Strack, P.R Winter, C.G Winter, S.S Larson, R.S Von Boehmer, H Look, A.T
author_sort	Sanda, T
title	Interconnecting molecular pathways in the pathogenesis and drug sensitivity of T-cell acute lymphoblastic leukemia
title_short	Interconnecting molecular pathways in the pathogenesis and drug sensitivity of T-cell acute lymphoblastic leukemia
title_full	Interconnecting molecular pathways in the pathogenesis and drug sensitivity of T-cell acute lymphoblastic leukemia
title_fullStr	Interconnecting molecular pathways in the pathogenesis and drug sensitivity of T-cell acute lymphoblastic leukemia
title_full_unstemmed	Interconnecting molecular pathways in the pathogenesis and drug sensitivity of T-cell acute lymphoblastic leukemia
title_sort	interconnecting molecular pathways in the pathogenesis and drug sensitivity of t-cell acute lymphoblastic leukemia
publisher	American Society of Hematology
publishDate	2020
url	https://scholarbank.nus.edu.sg/handle/10635/183915
_version_	1800914734660190208

Interconnecting molecular pathways in the pathogenesis and drug sensitivity of T-cell acute lymphoblastic leukemia

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