STAT3-And STAT5-dependent pathways competitively regulate the pan-differentiation of CD34 pos cells into tumor-competent dendritic cells

• Main Authors: Cohen, P.A, Koski, G.K, Czerniecki, B.J, Bunting, K.D, Fu, X.-Y, Wang, Z, Zhang, W.-J, Carter, C.S, Awad, M, Distel, C.A, Nagem, H, Paustian, C.C, Johnson, T.D, Tisdale, J.F, Shu, S
• Other Authors: BIOCHEMISTRY
• Format: Article
• Published: American Society of Hematology 2020
• Subjects: CD135 antigen; CD34 antigen; interferon regulatory factor; interleukin 12p70; interleukin 6; STAT3 protein; STAT5 protein; toll like receptor; transforming growth factor beta; flt3 ligand protein; membrane protein; recombinant granulocyte macrophage colony stimulating factor; Stat3 protein, mouse; animal cell; animal experiment; animal model; article; cell differentiation; cell function; cell maturation; cell polarity; cell proliferation; controlled study; cytokine production; dendritic cell; enzyme activation; enzyme inhibition; enzyme regulation; in vivo study; mouse; nonhuman; priority journal; protein interaction; signal transduction; adoptive immunotherapy; animal; Bagg albino mouse; bone marrow cell; C3H mouse; C57BL mouse; cytology; drug effect; experimental neoplasm; female; genetics; immunology; metabolism; mouse mutant; physiology; Animals; Antigens, CD34; Bone Marrow Cells; Cell Differentiation; Dendritic Cells; Female; Granulocyte Macrophage Colony-Stimulating Factors, Recombinant; Immunotherapy, Adoptive; Interleukin-6; Membrane Proteins; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Knockout; Neoplasms, Experimental; STAT3 Transcription Factor; STAT5 Transcription Factor
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/183926
• Institution: National University of Singapore

10.1182/blood-2007-12-130138