Impaired coupling of muscarinic M-1 receptors to G-proteins in the neocortex is associated with severity of dementia in Alzheimer's disease

• Main Authors: Tsang, Shirley WY, Lai, Mitchell KP, Kirvell, Sara, Francis, Paul T, Esiri, Margaret M, Hope, Tony, Chen, Christopher PL-H, Wong, Peter T-H
• Other Authors: PHARMACOLOGY
• Format: Article
• Language: English
• Published: ELSEVIER SCIENCE INC 2021
• Subjects: Science & Technology; Life Sciences & Biomedicine; Geriatrics & Gerontology; Neurosciences; Neurosciences & Neurology; muscarinic receptors; G-proteins; Alzheimer's disease; cognition; CHOLINE-ACETYLTRANSFERASE; ENTORHINAL CORTEX; SENILE DEMENTIA; TEMPORAL-LOBE; KINASE-C; BINDING; NEUROFIBRILLARY; ABNORMALITIES; THERAPIES; NEURONS
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/188372
• Institution: National University of Singapore

10.1016/j.neurobiolaging.2005.07.010