Development of a liver-specific Tet-off AAV8 vector for improved safety of insulin gene therapy for diabetes

Development of a liver-specific Tet-off AAV8 vector for improved safety of insulin gene therapy for diabetes

10.1002/jgm.3067

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Bibliographic Details
Main Authors: Gan, Shu Uin, Fu, Zhenying, Sia, Kian Chuan, Kon, Oi Lian, Calne, Roy, Lee, Kok Onn
Other Authors: MEDICINE
Format: Article
Language:English
Published: WILEY 2021
Subjects:
Science & Technology
Life Sciences & Biomedicine
Biotechnology & Applied Microbiology
Genetics & Heredity
Medicine, Research & Experimental
Research & Experimental Medicine
adeno-associated virus
diabetes
insulin
inducible
Tet-off
safety
SUBANTIMICROBIAL-DOSE DOXYCYCLINE
LONG-TERM SAFETY
INTRAMUSCULAR INJECTION
TETRACYCLINE
EXPRESSION
MICE
PROLIFERATION
TRANSGENE
EFFICACY
DELIVERY
Online Access:https://scholarbank.nus.edu.sg/handle/10635/205870
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Institution: National University of Singapore
Language: English

Internet

https://scholarbank.nus.edu.sg/handle/10635/205870

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