Development of a liver-specific Tet-off AAV8 vector for improved safety of insulin gene therapy for diabetes

10.1002/jgm.3067

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Main Authors:	Gan, Shu Uin, Fu, Zhenying, Sia, Kian Chuan, Kon, Oi Lian, Calne, Roy, Lee, Kok Onn
Other Authors:	MEDICINE
Format:	Article
Language:	English
Published:	WILEY 2021
Subjects:	Science & Technology Life Sciences & Biomedicine Biotechnology & Applied Microbiology Genetics & Heredity Medicine, Research & Experimental Research & Experimental Medicine adeno-associated virus diabetes insulin inducible Tet-off safety SUBANTIMICROBIAL-DOSE DOXYCYCLINE LONG-TERM SAFETY INTRAMUSCULAR INJECTION TETRACYCLINE EXPRESSION MICE PROLIFERATION TRANSGENE EFFICACY DELIVERY
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/205870
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Institution:	National University of Singapore
Language:	English

id	sg-nus-scholar.10635-205870
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spelling	sg-nus-scholar.10635-2058702024-04-25T01:21:55Z Development of a liver-specific Tet-off AAV8 vector for improved safety of insulin gene therapy for diabetes Gan, Shu Uin Fu, Zhenying Sia, Kian Chuan Kon, Oi Lian Calne, Roy Lee, Kok Onn MEDICINE SURGERY Science & Technology Life Sciences & Biomedicine Biotechnology & Applied Microbiology Genetics & Heredity Medicine, Research & Experimental Research & Experimental Medicine adeno-associated virus diabetes insulin inducible Tet-off safety SUBANTIMICROBIAL-DOSE DOXYCYCLINE LONG-TERM SAFETY INTRAMUSCULAR INJECTION TETRACYCLINE EXPRESSION MICE PROLIFERATION TRANSGENE EFFICACY DELIVERY 10.1002/jgm.3067 JOURNAL OF GENE MEDICINE 21 1 2021-11-11T04:38:45Z 2021-11-11T04:38:45Z 2019-01-01 2021-11-10T02:04:40Z Article Gan, Shu Uin, Fu, Zhenying, Sia, Kian Chuan, Kon, Oi Lian, Calne, Roy, Lee, Kok Onn (2019-01-01). Development of a liver-specific Tet-off AAV8 vector for improved safety of insulin gene therapy for diabetes. JOURNAL OF GENE MEDICINE 21 (1). ScholarBank@NUS Repository. https://doi.org/10.1002/jgm.3067 1099498X 15212254 https://scholarbank.nus.edu.sg/handle/10635/205870 en WILEY Elements
institution	National University of Singapore
building	NUS Library
continent	Asia
country	Singapore Singapore
content_provider	NUS Library
collection	ScholarBank@NUS
language	English
topic	Science & Technology Life Sciences & Biomedicine Biotechnology & Applied Microbiology Genetics & Heredity Medicine, Research & Experimental Research & Experimental Medicine adeno-associated virus diabetes insulin inducible Tet-off safety SUBANTIMICROBIAL-DOSE DOXYCYCLINE LONG-TERM SAFETY INTRAMUSCULAR INJECTION TETRACYCLINE EXPRESSION MICE PROLIFERATION TRANSGENE EFFICACY DELIVERY
spellingShingle	Science & Technology Life Sciences & Biomedicine Biotechnology & Applied Microbiology Genetics & Heredity Medicine, Research & Experimental Research & Experimental Medicine adeno-associated virus diabetes insulin inducible Tet-off safety SUBANTIMICROBIAL-DOSE DOXYCYCLINE LONG-TERM SAFETY INTRAMUSCULAR INJECTION TETRACYCLINE EXPRESSION MICE PROLIFERATION TRANSGENE EFFICACY DELIVERY Gan, Shu Uin Fu, Zhenying Sia, Kian Chuan Kon, Oi Lian Calne, Roy Lee, Kok Onn Development of a liver-specific Tet-off AAV8 vector for improved safety of insulin gene therapy for diabetes
description	10.1002/jgm.3067
author2	MEDICINE
author_facet	MEDICINE Gan, Shu Uin Fu, Zhenying Sia, Kian Chuan Kon, Oi Lian Calne, Roy Lee, Kok Onn
format	Article
author	Gan, Shu Uin Fu, Zhenying Sia, Kian Chuan Kon, Oi Lian Calne, Roy Lee, Kok Onn
author_sort	Gan, Shu Uin
title	Development of a liver-specific Tet-off AAV8 vector for improved safety of insulin gene therapy for diabetes
title_short	Development of a liver-specific Tet-off AAV8 vector for improved safety of insulin gene therapy for diabetes
title_full	Development of a liver-specific Tet-off AAV8 vector for improved safety of insulin gene therapy for diabetes
title_fullStr	Development of a liver-specific Tet-off AAV8 vector for improved safety of insulin gene therapy for diabetes
title_full_unstemmed	Development of a liver-specific Tet-off AAV8 vector for improved safety of insulin gene therapy for diabetes
title_sort	development of a liver-specific tet-off aav8 vector for improved safety of insulin gene therapy for diabetes
publisher	WILEY
publishDate	2021
url	https://scholarbank.nus.edu.sg/handle/10635/205870
_version_	1800915053245890560

Development of a liver-specific Tet-off AAV8 vector for improved safety of insulin gene therapy for diabetes

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