Overriding FUS autoregulation in mice triggers gain-of-toxic dysfunctions in RNA metabolism and autophagy-lysosome axis
10.7554/eLife.40811
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sg-nus-scholar.10635-2099992024-04-18T01:06:16Z Overriding FUS autoregulation in mice triggers gain-of-toxic dysfunctions in RNA metabolism and autophagy-lysosome axis Ling, S.-C. Dastidar, S.G. Tokunaga, S. Ho, W.Y. Lim, K. Ilieva, H. Parone, P.A. Tyan, S.-H. Tse, T.M. Chang, J.-C. Platoshyn, O. Bui, N.B. Bui, A. Vetto, A. Sun, S. McAlonis-Downes, M. Han, J.S. Swing, D. Kapeli, K. Yeo, G.W. Tessarollo, L. Marsala, M. Shaw, C.E. Tucker-Kellogg, G. La Spada, A.R. Lagier-Tourenne, C. Da Cruz, S. Cleveland, D.W. PHYSIOLOGY MEDICINE BIOLOGICAL SCIENCES amyotrophic lateral sclerosis (ALS) autophagy-lysosome frontotemporal degeneration (FTD) FUS homeostasis mouse neuroscience RNA metabolism 10.7554/eLife.40811 eLife 8 e40811 2021-12-09T03:06:09Z 2021-12-09T03:06:09Z 2019 Article Ling, S.-C., Dastidar, S.G., Tokunaga, S., Ho, W.Y., Lim, K., Ilieva, H., Parone, P.A., Tyan, S.-H., Tse, T.M., Chang, J.-C., Platoshyn, O., Bui, N.B., Bui, A., Vetto, A., Sun, S., McAlonis-Downes, M., Han, J.S., Swing, D., Kapeli, K., Yeo, G.W., Tessarollo, L., Marsala, M., Shaw, C.E., Tucker-Kellogg, G., La Spada, A.R., Lagier-Tourenne, C., Da Cruz, S., Cleveland, D.W. (2019). Overriding FUS autoregulation in mice triggers gain-of-toxic dysfunctions in RNA metabolism and autophagy-lysosome axis. eLife 8 : e40811. ScholarBank@NUS Repository. https://doi.org/10.7554/eLife.40811 2050-084X https://scholarbank.nus.edu.sg/handle/10635/209999 Attribution 4.0 International https://creativecommons.org/licenses/by/4.0/ NLM (Medline) Scopus OA2019 |
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amyotrophic lateral sclerosis (ALS) autophagy-lysosome frontotemporal degeneration (FTD) FUS homeostasis mouse neuroscience RNA metabolism |
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amyotrophic lateral sclerosis (ALS) autophagy-lysosome frontotemporal degeneration (FTD) FUS homeostasis mouse neuroscience RNA metabolism Ling, S.-C. Dastidar, S.G. Tokunaga, S. Ho, W.Y. Lim, K. Ilieva, H. Parone, P.A. Tyan, S.-H. Tse, T.M. Chang, J.-C. Platoshyn, O. Bui, N.B. Bui, A. Vetto, A. Sun, S. McAlonis-Downes, M. Han, J.S. Swing, D. Kapeli, K. Yeo, G.W. Tessarollo, L. Marsala, M. Shaw, C.E. Tucker-Kellogg, G. La Spada, A.R. Lagier-Tourenne, C. Da Cruz, S. Cleveland, D.W. Overriding FUS autoregulation in mice triggers gain-of-toxic dysfunctions in RNA metabolism and autophagy-lysosome axis |
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10.7554/eLife.40811 |
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PHYSIOLOGY |
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PHYSIOLOGY Ling, S.-C. Dastidar, S.G. Tokunaga, S. Ho, W.Y. Lim, K. Ilieva, H. Parone, P.A. Tyan, S.-H. Tse, T.M. Chang, J.-C. Platoshyn, O. Bui, N.B. Bui, A. Vetto, A. Sun, S. McAlonis-Downes, M. Han, J.S. Swing, D. Kapeli, K. Yeo, G.W. Tessarollo, L. Marsala, M. Shaw, C.E. Tucker-Kellogg, G. La Spada, A.R. Lagier-Tourenne, C. Da Cruz, S. Cleveland, D.W. |
format |
Article |
author |
Ling, S.-C. Dastidar, S.G. Tokunaga, S. Ho, W.Y. Lim, K. Ilieva, H. Parone, P.A. Tyan, S.-H. Tse, T.M. Chang, J.-C. Platoshyn, O. Bui, N.B. Bui, A. Vetto, A. Sun, S. McAlonis-Downes, M. Han, J.S. Swing, D. Kapeli, K. Yeo, G.W. Tessarollo, L. Marsala, M. Shaw, C.E. Tucker-Kellogg, G. La Spada, A.R. Lagier-Tourenne, C. Da Cruz, S. Cleveland, D.W. |
author_sort |
Ling, S.-C. |
title |
Overriding FUS autoregulation in mice triggers gain-of-toxic dysfunctions in RNA metabolism and autophagy-lysosome axis |
title_short |
Overriding FUS autoregulation in mice triggers gain-of-toxic dysfunctions in RNA metabolism and autophagy-lysosome axis |
title_full |
Overriding FUS autoregulation in mice triggers gain-of-toxic dysfunctions in RNA metabolism and autophagy-lysosome axis |
title_fullStr |
Overriding FUS autoregulation in mice triggers gain-of-toxic dysfunctions in RNA metabolism and autophagy-lysosome axis |
title_full_unstemmed |
Overriding FUS autoregulation in mice triggers gain-of-toxic dysfunctions in RNA metabolism and autophagy-lysosome axis |
title_sort |
overriding fus autoregulation in mice triggers gain-of-toxic dysfunctions in rna metabolism and autophagy-lysosome axis |
publisher |
NLM (Medline) |
publishDate |
2021 |
url |
https://scholarbank.nus.edu.sg/handle/10635/209999 |
_version_ |
1800915201392902144 |