Overriding FUS autoregulation in mice triggers gain-of-toxic dysfunctions in RNA metabolism and autophagy-lysosome axis

10.7554/eLife.40811

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Main Authors: Ling, S.-C., Dastidar, S.G., Tokunaga, S., Ho, W.Y., Lim, K., Ilieva, H., Parone, P.A., Tyan, S.-H., Tse, T.M., Chang, J.-C., Platoshyn, O., Bui, N.B., Bui, A., Vetto, A., Sun, S., McAlonis-Downes, M., Han, J.S., Swing, D., Kapeli, K., Yeo, G.W., Tessarollo, L., Marsala, M., Shaw, C.E., Tucker-Kellogg, G., La Spada, A.R., Lagier-Tourenne, C., Da Cruz, S., Cleveland, D.W.
Other Authors: PHYSIOLOGY
Format: Article
Published: NLM (Medline) 2021
Subjects:
FUS
Online Access:https://scholarbank.nus.edu.sg/handle/10635/209999
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spelling sg-nus-scholar.10635-2099992024-04-18T01:06:16Z Overriding FUS autoregulation in mice triggers gain-of-toxic dysfunctions in RNA metabolism and autophagy-lysosome axis Ling, S.-C. Dastidar, S.G. Tokunaga, S. Ho, W.Y. Lim, K. Ilieva, H. Parone, P.A. Tyan, S.-H. Tse, T.M. Chang, J.-C. Platoshyn, O. Bui, N.B. Bui, A. Vetto, A. Sun, S. McAlonis-Downes, M. Han, J.S. Swing, D. Kapeli, K. Yeo, G.W. Tessarollo, L. Marsala, M. Shaw, C.E. Tucker-Kellogg, G. La Spada, A.R. Lagier-Tourenne, C. Da Cruz, S. Cleveland, D.W. PHYSIOLOGY MEDICINE BIOLOGICAL SCIENCES amyotrophic lateral sclerosis (ALS) autophagy-lysosome frontotemporal degeneration (FTD) FUS homeostasis mouse neuroscience RNA metabolism 10.7554/eLife.40811 eLife 8 e40811 2021-12-09T03:06:09Z 2021-12-09T03:06:09Z 2019 Article Ling, S.-C., Dastidar, S.G., Tokunaga, S., Ho, W.Y., Lim, K., Ilieva, H., Parone, P.A., Tyan, S.-H., Tse, T.M., Chang, J.-C., Platoshyn, O., Bui, N.B., Bui, A., Vetto, A., Sun, S., McAlonis-Downes, M., Han, J.S., Swing, D., Kapeli, K., Yeo, G.W., Tessarollo, L., Marsala, M., Shaw, C.E., Tucker-Kellogg, G., La Spada, A.R., Lagier-Tourenne, C., Da Cruz, S., Cleveland, D.W. (2019). Overriding FUS autoregulation in mice triggers gain-of-toxic dysfunctions in RNA metabolism and autophagy-lysosome axis. eLife 8 : e40811. ScholarBank@NUS Repository. https://doi.org/10.7554/eLife.40811 2050-084X https://scholarbank.nus.edu.sg/handle/10635/209999 Attribution 4.0 International https://creativecommons.org/licenses/by/4.0/ NLM (Medline) Scopus OA2019
institution National University of Singapore
building NUS Library
continent Asia
country Singapore
Singapore
content_provider NUS Library
collection ScholarBank@NUS
topic amyotrophic lateral sclerosis (ALS)
autophagy-lysosome
frontotemporal degeneration (FTD)
FUS
homeostasis
mouse
neuroscience
RNA metabolism
spellingShingle amyotrophic lateral sclerosis (ALS)
autophagy-lysosome
frontotemporal degeneration (FTD)
FUS
homeostasis
mouse
neuroscience
RNA metabolism
Ling, S.-C.
Dastidar, S.G.
Tokunaga, S.
Ho, W.Y.
Lim, K.
Ilieva, H.
Parone, P.A.
Tyan, S.-H.
Tse, T.M.
Chang, J.-C.
Platoshyn, O.
Bui, N.B.
Bui, A.
Vetto, A.
Sun, S.
McAlonis-Downes, M.
Han, J.S.
Swing, D.
Kapeli, K.
Yeo, G.W.
Tessarollo, L.
Marsala, M.
Shaw, C.E.
Tucker-Kellogg, G.
La Spada, A.R.
Lagier-Tourenne, C.
Da Cruz, S.
Cleveland, D.W.
Overriding FUS autoregulation in mice triggers gain-of-toxic dysfunctions in RNA metabolism and autophagy-lysosome axis
description 10.7554/eLife.40811
author2 PHYSIOLOGY
author_facet PHYSIOLOGY
Ling, S.-C.
Dastidar, S.G.
Tokunaga, S.
Ho, W.Y.
Lim, K.
Ilieva, H.
Parone, P.A.
Tyan, S.-H.
Tse, T.M.
Chang, J.-C.
Platoshyn, O.
Bui, N.B.
Bui, A.
Vetto, A.
Sun, S.
McAlonis-Downes, M.
Han, J.S.
Swing, D.
Kapeli, K.
Yeo, G.W.
Tessarollo, L.
Marsala, M.
Shaw, C.E.
Tucker-Kellogg, G.
La Spada, A.R.
Lagier-Tourenne, C.
Da Cruz, S.
Cleveland, D.W.
format Article
author Ling, S.-C.
Dastidar, S.G.
Tokunaga, S.
Ho, W.Y.
Lim, K.
Ilieva, H.
Parone, P.A.
Tyan, S.-H.
Tse, T.M.
Chang, J.-C.
Platoshyn, O.
Bui, N.B.
Bui, A.
Vetto, A.
Sun, S.
McAlonis-Downes, M.
Han, J.S.
Swing, D.
Kapeli, K.
Yeo, G.W.
Tessarollo, L.
Marsala, M.
Shaw, C.E.
Tucker-Kellogg, G.
La Spada, A.R.
Lagier-Tourenne, C.
Da Cruz, S.
Cleveland, D.W.
author_sort Ling, S.-C.
title Overriding FUS autoregulation in mice triggers gain-of-toxic dysfunctions in RNA metabolism and autophagy-lysosome axis
title_short Overriding FUS autoregulation in mice triggers gain-of-toxic dysfunctions in RNA metabolism and autophagy-lysosome axis
title_full Overriding FUS autoregulation in mice triggers gain-of-toxic dysfunctions in RNA metabolism and autophagy-lysosome axis
title_fullStr Overriding FUS autoregulation in mice triggers gain-of-toxic dysfunctions in RNA metabolism and autophagy-lysosome axis
title_full_unstemmed Overriding FUS autoregulation in mice triggers gain-of-toxic dysfunctions in RNA metabolism and autophagy-lysosome axis
title_sort overriding fus autoregulation in mice triggers gain-of-toxic dysfunctions in rna metabolism and autophagy-lysosome axis
publisher NLM (Medline)
publishDate 2021
url https://scholarbank.nus.edu.sg/handle/10635/209999
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