Liver fibrosis and CD206<sup>+</sup> macrophage accumulation are suppressed by anti-GM-CSF therapy

10.1016/j.jhepr.2019.11.006

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Main Authors:	Tan-Garcia, A, Lai, F, Sheng Yeong, JP, Irac, SE, Ng, PY, Msallam, R, Tatt Lim, JC, Wai, LE, Tham, CYL, Choo, SP, Lim, T, Young, DY, D'Ambrosio, R, Degasperi, E, Perbellini, R, Newell, E, Le Bert, N, Ginhoux, F, Bertoletti, A, Chen, Q, Dutertre, CA
Other Authors:	DEAN'S OFFICE (DUKE-NUS MEDICAL SCHOOL)
Format:	Article
Published:	Elsevier BV 2022
Subjects:	ALT, alanine aminotransferase BAMBI, BMP and Activin Membrane-bound Inhibitor CD206+ macrophages DAA, direct-acting antiviral DC, dendritic cell FFPE, formalin-fixed paraffin-embedded GM-CSF GM-CSF, granulocyte-macrophage colony-stimulating factor HCC, hepatocellular carcinoma HCV HIER, heat-induced epitope retrieval HSC, hepatic stellate cells ICS, intracellular cytokine staining Intrahepatic macrophages LPS, lipopolysaccharide LSM, liver stiffness measurement MS, multiple sclerosis NASH NASH, non-alcoholic steatohepatitis PBMCs, peripheral blood mononuclear cells RA, rheumatoid arthritis SVR, sustained virological response TCR, T cell receptor TMA, tissue microarray TNFα, tumour necrosis factor-α TSA, tyramide signal amplification anti-GM-CSF neutralizing antibody fibrosis moMΦs, monocyte-derived macrophage-like cells t-SNE, t-distributed stochastic neighbour embedding
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/212796
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Institution:	National University of Singapore

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spelling	sg-nus-scholar.10635-2127962024-04-18T03:05:17Z Liver fibrosis and CD206<sup>+</sup> macrophage accumulation are suppressed by anti-GM-CSF therapy Tan-Garcia, A Lai, F Sheng Yeong, JP Irac, SE Ng, PY Msallam, R Tatt Lim, JC Wai, LE Tham, CYL Choo, SP Lim, T Young, DY D'Ambrosio, R Degasperi, E Perbellini, R Newell, E Le Bert, N Ginhoux, F Bertoletti, A Chen, Q Dutertre, CA DEAN'S OFFICE (DUKE-NUS MEDICAL SCHOOL) MEDICINE MICROBIOLOGY AND IMMUNOLOGY DUKE-NUS MEDICAL SCHOOL ALT, alanine aminotransferase BAMBI, BMP and Activin Membrane-bound Inhibitor CD206+ macrophages DAA, direct-acting antiviral DC, dendritic cell FFPE, formalin-fixed paraffin-embedded GM-CSF GM-CSF, granulocyte-macrophage colony-stimulating factor HCC, hepatocellular carcinoma HCV HIER, heat-induced epitope retrieval HSC, hepatic stellate cells ICS, intracellular cytokine staining Intrahepatic macrophages LPS, lipopolysaccharide LSM, liver stiffness measurement MS, multiple sclerosis NASH NASH, non-alcoholic steatohepatitis PBMCs, peripheral blood mononuclear cells RA, rheumatoid arthritis SVR, sustained virological response TCR, T cell receptor TMA, tissue microarray TNFα, tumour necrosis factor-α TSA, tyramide signal amplification anti-GM-CSF neutralizing antibody fibrosis moMΦs, monocyte-derived macrophage-like cells t-SNE, t-distributed stochastic neighbour embedding 10.1016/j.jhepr.2019.11.006 JHEP Reports 2 1 100062- 2022-01-03T05:44:38Z 2022-01-03T05:44:38Z 2020-02-01 2021-12-30T08:40:10Z Article Tan-Garcia, A, Lai, F, Sheng Yeong, JP, Irac, SE, Ng, PY, Msallam, R, Tatt Lim, JC, Wai, LE, Tham, CYL, Choo, SP, Lim, T, Young, DY, D'Ambrosio, R, Degasperi, E, Perbellini, R, Newell, E, Le Bert, N, Ginhoux, F, Bertoletti, A, Chen, Q, Dutertre, CA (2020-02-01). Liver fibrosis and CD206<sup>+</sup> macrophage accumulation are suppressed by anti-GM-CSF therapy. JHEP Reports 2 (1) : 100062-. ScholarBank@NUS Repository. https://doi.org/10.1016/j.jhepr.2019.11.006 25895559 https://scholarbank.nus.edu.sg/handle/10635/212796 Elsevier BV Elements
institution	National University of Singapore
building	NUS Library
continent	Asia
country	Singapore Singapore
content_provider	NUS Library
collection	ScholarBank@NUS
topic	ALT, alanine aminotransferase BAMBI, BMP and Activin Membrane-bound Inhibitor CD206+ macrophages DAA, direct-acting antiviral DC, dendritic cell FFPE, formalin-fixed paraffin-embedded GM-CSF GM-CSF, granulocyte-macrophage colony-stimulating factor HCC, hepatocellular carcinoma HCV HIER, heat-induced epitope retrieval HSC, hepatic stellate cells ICS, intracellular cytokine staining Intrahepatic macrophages LPS, lipopolysaccharide LSM, liver stiffness measurement MS, multiple sclerosis NASH NASH, non-alcoholic steatohepatitis PBMCs, peripheral blood mononuclear cells RA, rheumatoid arthritis SVR, sustained virological response TCR, T cell receptor TMA, tissue microarray TNFα, tumour necrosis factor-α TSA, tyramide signal amplification anti-GM-CSF neutralizing antibody fibrosis moMΦs, monocyte-derived macrophage-like cells t-SNE, t-distributed stochastic neighbour embedding
spellingShingle	ALT, alanine aminotransferase BAMBI, BMP and Activin Membrane-bound Inhibitor CD206+ macrophages DAA, direct-acting antiviral DC, dendritic cell FFPE, formalin-fixed paraffin-embedded GM-CSF GM-CSF, granulocyte-macrophage colony-stimulating factor HCC, hepatocellular carcinoma HCV HIER, heat-induced epitope retrieval HSC, hepatic stellate cells ICS, intracellular cytokine staining Intrahepatic macrophages LPS, lipopolysaccharide LSM, liver stiffness measurement MS, multiple sclerosis NASH NASH, non-alcoholic steatohepatitis PBMCs, peripheral blood mononuclear cells RA, rheumatoid arthritis SVR, sustained virological response TCR, T cell receptor TMA, tissue microarray TNFα, tumour necrosis factor-α TSA, tyramide signal amplification anti-GM-CSF neutralizing antibody fibrosis moMΦs, monocyte-derived macrophage-like cells t-SNE, t-distributed stochastic neighbour embedding Tan-Garcia, A Lai, F Sheng Yeong, JP Irac, SE Ng, PY Msallam, R Tatt Lim, JC Wai, LE Tham, CYL Choo, SP Lim, T Young, DY D'Ambrosio, R Degasperi, E Perbellini, R Newell, E Le Bert, N Ginhoux, F Bertoletti, A Chen, Q Dutertre, CA Liver fibrosis and CD206<sup>+</sup> macrophage accumulation are suppressed by anti-GM-CSF therapy
description	10.1016/j.jhepr.2019.11.006
author2	DEAN'S OFFICE (DUKE-NUS MEDICAL SCHOOL)
author_facet	DEAN'S OFFICE (DUKE-NUS MEDICAL SCHOOL) Tan-Garcia, A Lai, F Sheng Yeong, JP Irac, SE Ng, PY Msallam, R Tatt Lim, JC Wai, LE Tham, CYL Choo, SP Lim, T Young, DY D'Ambrosio, R Degasperi, E Perbellini, R Newell, E Le Bert, N Ginhoux, F Bertoletti, A Chen, Q Dutertre, CA
format	Article
author	Tan-Garcia, A Lai, F Sheng Yeong, JP Irac, SE Ng, PY Msallam, R Tatt Lim, JC Wai, LE Tham, CYL Choo, SP Lim, T Young, DY D'Ambrosio, R Degasperi, E Perbellini, R Newell, E Le Bert, N Ginhoux, F Bertoletti, A Chen, Q Dutertre, CA
author_sort	Tan-Garcia, A
title	Liver fibrosis and CD206<sup>+</sup> macrophage accumulation are suppressed by anti-GM-CSF therapy
title_short	Liver fibrosis and CD206<sup>+</sup> macrophage accumulation are suppressed by anti-GM-CSF therapy
title_full	Liver fibrosis and CD206<sup>+</sup> macrophage accumulation are suppressed by anti-GM-CSF therapy
title_fullStr	Liver fibrosis and CD206<sup>+</sup> macrophage accumulation are suppressed by anti-GM-CSF therapy
title_full_unstemmed	Liver fibrosis and CD206<sup>+</sup> macrophage accumulation are suppressed by anti-GM-CSF therapy
title_sort	liver fibrosis and cd206<sup>+</sup> macrophage accumulation are suppressed by anti-gm-csf therapy
publisher	Elsevier BV
publishDate	2022
url	https://scholarbank.nus.edu.sg/handle/10635/212796
_version_	1800915291893399552

Liver fibrosis and CD206<sup>+</sup> macrophage accumulation are suppressed by anti-GM-CSF therapy

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