JAK inhibition reduces SARS-CoV-2 liver infectivity and modulates inflammatory responses to reduce morbidity and mortality

• Main Authors: Stebbing, Justin, Nievas, Gines Sanchez, Falcone, Marco, Youhanna, Sonia, Richardson, Peter, Ottaviani, Silvia, Shen, Joanne X, Sommerauer, Christian, Tiseo, Giusy, Ghiadoni, Lorenzo, Virdis, Agostino, Monzani, Fabio, Rizos, Luis Romero, Forfori, Francesco, Avendano-Cespedes, Almudena, De Marco, Salvatore, Carrozzi, Laura, Lena, Fabio, Sanchez-Jurado, Pedro Manuel, Lacerenza, Leonardo Gianluca, Cesira, Nencioni, Caldevilla-Bernardo, David, Perrella, Antonio, Niccoli, Laura, Mendez, Lourdes Saez, Matarrese, Daniela, Goletti, Delia, Tan, Yee-Joo, Monteil, Vanessa, Dranitsaris, George, Cantini, Fabrizio, Farcomeni, Alessio, Dutta, Shuchismita, Burley, Stephen K, Zhang, Haibo, Pistello, Mauro, Li, William, Romero, Marta Mas, Pretel, Fernando Andres, Simon-Talero, Rafaela Sanchez, Garcia-Molina, Rafael, Kutter, Claudia, Felce, James H, Nizami, Zehra F, Miklosi, Andras G, Penninger, Josef M, Menichetti, Francesco, Mirazimi, Ali, Abizanda, Pedro, Lauschke, Volker M
• Other Authors: MICROBIOLOGY AND IMMUNOLOGY
• Format: Article
• Language: English
• Published: AMER ASSOC ADVANCEMENT SCIENCE 2022
• Subjects: Science & Technology; Multidisciplinary Sciences; Science & Technology - Other Topics; RHEUMATOID-ARTHRITIS; FUNCTIONAL RECEPTOR; BARICITINIB; PLACEBO; PROTEIN; INJURY
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/219373
• Institution: National University of Singapore

10.1126/sciadv.abe4724