Symmetric activation and modulation of the human calcium-sensing receptor

10.1073/pnas.2115849118

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Main Authors:	Park, J, Zuo, H, Frangaj, A, Fu, Z, Yen, LY, Zhang, Z, Mosyak, L, Slavkovich, VN, Liu, J, Ray, KM, Cao, B, Vallese, F, Geng, Y, Chen, S, Grassucci, R, Dandey, VP, Tan, YZ, Eng, E, Lee, Y, Kloss, B, Liu, Z, Hendrickson, WA, Potter, CS, Carragher, B, Graziano, J, Conigrave, AD, Frank, J, Clarke, OB, Fan, QR
Other Authors:	BIOLOGICAL SCIENCES
Format:	Article
Published:	Proceedings of the National Academy of Sciences 2022
Subjects:	activation mechanism allosteric modulation calcium-sensing receptor cryo-EM structure symmetry Calcium Cryoelectron Microscopy Gene Expression Regulation HEK293 Cells Homeostasis Humans Models, Molecular Protein Conformation Protein Domains Receptors, Calcium-Sensing Signal Transduction
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/227196
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Institution:	National University of Singapore

id	sg-nus-scholar.10635-227196
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spelling	sg-nus-scholar.10635-2271962024-04-02T08:13:26Z Symmetric activation and modulation of the human calcium-sensing receptor Park, J Zuo, H Frangaj, A Fu, Z Yen, LY Zhang, Z Mosyak, L Slavkovich, VN Liu, J Ray, KM Cao, B Vallese, F Geng, Y Chen, S Grassucci, R Dandey, VP Tan, YZ Eng, E Lee, Y Kloss, B Liu, Z Hendrickson, WA Potter, CS Carragher, B Graziano, J Conigrave, AD Frank, J Clarke, OB Fan, QR BIOLOGICAL SCIENCES activation mechanism allosteric modulation calcium-sensing receptor cryo-EM structure symmetry Calcium Cryoelectron Microscopy Gene Expression Regulation HEK293 Cells Homeostasis Humans Models, Molecular Protein Conformation Protein Domains Receptors, Calcium-Sensing Signal Transduction 10.1073/pnas.2115849118 Proceedings of the National Academy of Sciences of the United States of America 118 51 e2115849118- 2022-06-20T02:01:35Z 2022-06-20T02:01:35Z 2021-12-21 2022-06-18T14:48:59Z Article Park, J, Zuo, H, Frangaj, A, Fu, Z, Yen, LY, Zhang, Z, Mosyak, L, Slavkovich, VN, Liu, J, Ray, KM, Cao, B, Vallese, F, Geng, Y, Chen, S, Grassucci, R, Dandey, VP, Tan, YZ, Eng, E, Lee, Y, Kloss, B, Liu, Z, Hendrickson, WA, Potter, CS, Carragher, B, Graziano, J, Conigrave, AD, Frank, J, Clarke, OB, Fan, QR (2021-12-21). Symmetric activation and modulation of the human calcium-sensing receptor. Proceedings of the National Academy of Sciences of the United States of America 118 (51) : e2115849118-. ScholarBank@NUS Repository. https://doi.org/10.1073/pnas.2115849118 00278424 10916490 https://scholarbank.nus.edu.sg/handle/10635/227196 Proceedings of the National Academy of Sciences Elements
institution	National University of Singapore
building	NUS Library
continent	Asia
country	Singapore Singapore
content_provider	NUS Library
collection	ScholarBank@NUS
topic	activation mechanism allosteric modulation calcium-sensing receptor cryo-EM structure symmetry Calcium Cryoelectron Microscopy Gene Expression Regulation HEK293 Cells Homeostasis Humans Models, Molecular Protein Conformation Protein Domains Receptors, Calcium-Sensing Signal Transduction
spellingShingle	activation mechanism allosteric modulation calcium-sensing receptor cryo-EM structure symmetry Calcium Cryoelectron Microscopy Gene Expression Regulation HEK293 Cells Homeostasis Humans Models, Molecular Protein Conformation Protein Domains Receptors, Calcium-Sensing Signal Transduction Park, J Zuo, H Frangaj, A Fu, Z Yen, LY Zhang, Z Mosyak, L Slavkovich, VN Liu, J Ray, KM Cao, B Vallese, F Geng, Y Chen, S Grassucci, R Dandey, VP Tan, YZ Eng, E Lee, Y Kloss, B Liu, Z Hendrickson, WA Potter, CS Carragher, B Graziano, J Conigrave, AD Frank, J Clarke, OB Fan, QR Symmetric activation and modulation of the human calcium-sensing receptor
description	10.1073/pnas.2115849118
author2	BIOLOGICAL SCIENCES
author_facet	BIOLOGICAL SCIENCES Park, J Zuo, H Frangaj, A Fu, Z Yen, LY Zhang, Z Mosyak, L Slavkovich, VN Liu, J Ray, KM Cao, B Vallese, F Geng, Y Chen, S Grassucci, R Dandey, VP Tan, YZ Eng, E Lee, Y Kloss, B Liu, Z Hendrickson, WA Potter, CS Carragher, B Graziano, J Conigrave, AD Frank, J Clarke, OB Fan, QR
format	Article
author	Park, J Zuo, H Frangaj, A Fu, Z Yen, LY Zhang, Z Mosyak, L Slavkovich, VN Liu, J Ray, KM Cao, B Vallese, F Geng, Y Chen, S Grassucci, R Dandey, VP Tan, YZ Eng, E Lee, Y Kloss, B Liu, Z Hendrickson, WA Potter, CS Carragher, B Graziano, J Conigrave, AD Frank, J Clarke, OB Fan, QR
author_sort	Park, J
title	Symmetric activation and modulation of the human calcium-sensing receptor
title_short	Symmetric activation and modulation of the human calcium-sensing receptor
title_full	Symmetric activation and modulation of the human calcium-sensing receptor
title_fullStr	Symmetric activation and modulation of the human calcium-sensing receptor
title_full_unstemmed	Symmetric activation and modulation of the human calcium-sensing receptor
title_sort	symmetric activation and modulation of the human calcium-sensing receptor
publisher	Proceedings of the National Academy of Sciences
publishDate	2022
url	https://scholarbank.nus.edu.sg/handle/10635/227196
_version_	1795301786531135488

Symmetric activation and modulation of the human calcium-sensing receptor

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