ISM1 protects lung homeostasis via cell-surface GRP78-mediated alveolar macrophage apoptosis

10.1073/pnas.2019161119

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Main Authors:	Lam, TYW, Nguyen, N, Peh, HY, Shanmugasundaram, M, Chandna, R, Tee, JH, Ong, CB, Hossain, MZ, Venugopal, S, Zhang, T, Xu, S, Qiu, T, Kong, WT, Chakarov, S, Srivastava, S, Liao, W, Kim, JS, Ming Teh, Ginhoux, F, Wong, WSF, Ge, R
Other Authors:	PHARMACOLOGY
Format:	Article
Published:	Proceedings of the National Academy of Sciences 2022
Subjects:	ISM1 alveolar macrophages apoptosis cell surface GRP78 chronic obstructive pulmonary disease Alveolar Epithelial Cells Animals Apoptosis Bronchoalveolar Lavage Fluid Disease Models, Animal Endoplasmic Reticulum Chaperone BiP Female Homeostasis Inflammation Intercellular Signaling Peptides and Proteins Lung Macrophages, Alveolar Male Mice Mice, Inbred BALB C Phagocytosis Pulmonary Disease, Chronic Obstructive Pulmonary Emphysema Smoke Smoking Tobacco
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/229045
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Institution:	National University of Singapore

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spelling	sg-nus-scholar.10635-2290452024-11-15T16:12:46Z ISM1 protects lung homeostasis via cell-surface GRP78-mediated alveolar macrophage apoptosis Lam, TYW Nguyen, N Peh, HY Shanmugasundaram, M Chandna, R Tee, JH Ong, CB Hossain, MZ Venugopal, S Zhang, T Xu, S Qiu, T Kong, WT Chakarov, S Srivastava, S Liao, W Kim, JS Ming Teh Ginhoux, F Wong, WSF Ge, R PHARMACOLOGY MEDICINE PHYSIOLOGY CANCER SCIENCE INSTITUTE OF SINGAPORE BIOLOGICAL SCIENCES PATHOLOGY Prof Wai-Shiu Fred Wong ISM1 alveolar macrophages apoptosis cell surface GRP78 chronic obstructive pulmonary disease Alveolar Epithelial Cells Animals Apoptosis Bronchoalveolar Lavage Fluid Disease Models, Animal Endoplasmic Reticulum Chaperone BiP Female Homeostasis Inflammation Intercellular Signaling Peptides and Proteins Lung Macrophages, Alveolar Male Mice Mice, Inbred BALB C Phagocytosis Pulmonary Disease, Chronic Obstructive Pulmonary Emphysema Smoke Smoking Tobacco 10.1073/pnas.2019161119 Proceedings of the National Academy of Sciences of the United States of America 119 4 e2019161119- 2022-07-22T02:15:13Z 2022-07-22T02:15:13Z 2022-01-25 2022-07-17T03:43:41Z Article Lam, TYW, Nguyen, N, Peh, HY, Shanmugasundaram, M, Chandna, R, Tee, JH, Ong, CB, Hossain, MZ, Venugopal, S, Zhang, T, Xu, S, Qiu, T, Kong, WT, Chakarov, S, Srivastava, S, Liao, W, Kim, JS, Ming Teh, Ginhoux, F, Wong, WSF, Ge, R (2022-01-25). ISM1 protects lung homeostasis via cell-surface GRP78-mediated alveolar macrophage apoptosis. Proceedings of the National Academy of Sciences of the United States of America 119 (4) : e2019161119-. ScholarBank@NUS Repository. https://doi.org/10.1073/pnas.2019161119 00278424 10916490 https://scholarbank.nus.edu.sg/handle/10635/229045 Proceedings of the National Academy of Sciences Elements
institution	National University of Singapore
building	NUS Library
continent	Asia
country	Singapore Singapore
content_provider	NUS Library
collection	ScholarBank@NUS
topic	ISM1 alveolar macrophages apoptosis cell surface GRP78 chronic obstructive pulmonary disease Alveolar Epithelial Cells Animals Apoptosis Bronchoalveolar Lavage Fluid Disease Models, Animal Endoplasmic Reticulum Chaperone BiP Female Homeostasis Inflammation Intercellular Signaling Peptides and Proteins Lung Macrophages, Alveolar Male Mice Mice, Inbred BALB C Phagocytosis Pulmonary Disease, Chronic Obstructive Pulmonary Emphysema Smoke Smoking Tobacco
spellingShingle	ISM1 alveolar macrophages apoptosis cell surface GRP78 chronic obstructive pulmonary disease Alveolar Epithelial Cells Animals Apoptosis Bronchoalveolar Lavage Fluid Disease Models, Animal Endoplasmic Reticulum Chaperone BiP Female Homeostasis Inflammation Intercellular Signaling Peptides and Proteins Lung Macrophages, Alveolar Male Mice Mice, Inbred BALB C Phagocytosis Pulmonary Disease, Chronic Obstructive Pulmonary Emphysema Smoke Smoking Tobacco Lam, TYW Nguyen, N Peh, HY Shanmugasundaram, M Chandna, R Tee, JH Ong, CB Hossain, MZ Venugopal, S Zhang, T Xu, S Qiu, T Kong, WT Chakarov, S Srivastava, S Liao, W Kim, JS Ming Teh Ginhoux, F Wong, WSF Ge, R ISM1 protects lung homeostasis via cell-surface GRP78-mediated alveolar macrophage apoptosis
description	10.1073/pnas.2019161119
author2	PHARMACOLOGY
author_facet	PHARMACOLOGY Lam, TYW Nguyen, N Peh, HY Shanmugasundaram, M Chandna, R Tee, JH Ong, CB Hossain, MZ Venugopal, S Zhang, T Xu, S Qiu, T Kong, WT Chakarov, S Srivastava, S Liao, W Kim, JS Ming Teh Ginhoux, F Wong, WSF Ge, R
format	Article
author	Lam, TYW Nguyen, N Peh, HY Shanmugasundaram, M Chandna, R Tee, JH Ong, CB Hossain, MZ Venugopal, S Zhang, T Xu, S Qiu, T Kong, WT Chakarov, S Srivastava, S Liao, W Kim, JS Ming Teh Ginhoux, F Wong, WSF Ge, R
author_sort	Lam, TYW
title	ISM1 protects lung homeostasis via cell-surface GRP78-mediated alveolar macrophage apoptosis
title_short	ISM1 protects lung homeostasis via cell-surface GRP78-mediated alveolar macrophage apoptosis
title_full	ISM1 protects lung homeostasis via cell-surface GRP78-mediated alveolar macrophage apoptosis
title_fullStr	ISM1 protects lung homeostasis via cell-surface GRP78-mediated alveolar macrophage apoptosis
title_full_unstemmed	ISM1 protects lung homeostasis via cell-surface GRP78-mediated alveolar macrophage apoptosis
title_sort	ism1 protects lung homeostasis via cell-surface grp78-mediated alveolar macrophage apoptosis
publisher	Proceedings of the National Academy of Sciences
publishDate	2022
url	https://scholarbank.nus.edu.sg/handle/10635/229045
_version_	1821214973400973312

ISM1 protects lung homeostasis via cell-surface GRP78-mediated alveolar macrophage apoptosis

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