Expression of a constitutively active p38α mutant in mice causes early death, anemia, and accumulation of immunosuppressive cells

• Main Authors: Darlyuk-Saadon, I, Heng, CKM, Bai, C, Gilad, N, Yu, WP, Meng Huang Mok, M, Wong, WSF, Engelberg, D
• Other Authors: CANCER SCIENCE INSTITUTE OF SINGAPORE
• Format: Article
• Published: Wiley 2022
• Subjects: active variants; anemia; immunosuppressive cells; p38α; transgenic mouse; Anemia; Animals; Body Weight; Cytokines; Gene Expression Regulation, Enzymologic; Intracellular Signaling Peptides and Proteins; Macrophages; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Mitogen-Activated Protein Kinase 14; Mutation; Myeloid-Derived Suppressor Cells; Protein Serine-Threonine Kinases; Substrate Specificity
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/229047
• Institution: National University of Singapore

10.1111/febs.15697