Targeted integration of EpCAM-specific CAR in human induced pluripotent stem cells and their differentiation into NK cells
10.1186/s13287-021-02648-4
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2022
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sg-nus-scholar.10635-2335322024-04-02T08:10:38Z Targeted integration of EpCAM-specific CAR in human induced pluripotent stem cells and their differentiation into NK cells Tang, Shin Yi Zha, Shijun Du, Zhicheng Zeng, Jieming Zhu, Detu Luo, Yumei Wang, Shu BIOLOGICAL SCIENCES Adeno-associated virus integration site 1 (AAVS1) Chimeric antigen receptors (CAR) Epithelial cell adhesion molecule (EpCAM) Genetic engineering Immunotherapy Induced pluripotent stem cells (iPSC) Natural killer cells (NK) NK differentiation Targeted integration Zinc finger nuclease (ZFN) 10.1186/s13287-021-02648-4 Stem Cell Research and Therapy 12 1 580 2022-10-26T09:00:44Z 2022-10-26T09:00:44Z 2021-11-21 Article Tang, Shin Yi, Zha, Shijun, Du, Zhicheng, Zeng, Jieming, Zhu, Detu, Luo, Yumei, Wang, Shu (2021-11-21). Targeted integration of EpCAM-specific CAR in human induced pluripotent stem cells and their differentiation into NK cells. Stem Cell Research and Therapy 12 (1) : 580. ScholarBank@NUS Repository. https://doi.org/10.1186/s13287-021-02648-4 1757-6512 https://scholarbank.nus.edu.sg/handle/10635/233532 Attribution 4.0 International https://creativecommons.org/licenses/by/4.0/ BioMed Central Ltd Scopus OA2021 |
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Adeno-associated virus integration site 1 (AAVS1) Chimeric antigen receptors (CAR) Epithelial cell adhesion molecule (EpCAM) Genetic engineering Immunotherapy Induced pluripotent stem cells (iPSC) Natural killer cells (NK) NK differentiation Targeted integration Zinc finger nuclease (ZFN) |
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Adeno-associated virus integration site 1 (AAVS1) Chimeric antigen receptors (CAR) Epithelial cell adhesion molecule (EpCAM) Genetic engineering Immunotherapy Induced pluripotent stem cells (iPSC) Natural killer cells (NK) NK differentiation Targeted integration Zinc finger nuclease (ZFN) Tang, Shin Yi Zha, Shijun Du, Zhicheng Zeng, Jieming Zhu, Detu Luo, Yumei Wang, Shu Targeted integration of EpCAM-specific CAR in human induced pluripotent stem cells and their differentiation into NK cells |
description |
10.1186/s13287-021-02648-4 |
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BIOLOGICAL SCIENCES |
author_facet |
BIOLOGICAL SCIENCES Tang, Shin Yi Zha, Shijun Du, Zhicheng Zeng, Jieming Zhu, Detu Luo, Yumei Wang, Shu |
format |
Article |
author |
Tang, Shin Yi Zha, Shijun Du, Zhicheng Zeng, Jieming Zhu, Detu Luo, Yumei Wang, Shu |
author_sort |
Tang, Shin Yi |
title |
Targeted integration of EpCAM-specific CAR in human induced pluripotent stem cells and their differentiation into NK cells |
title_short |
Targeted integration of EpCAM-specific CAR in human induced pluripotent stem cells and their differentiation into NK cells |
title_full |
Targeted integration of EpCAM-specific CAR in human induced pluripotent stem cells and their differentiation into NK cells |
title_fullStr |
Targeted integration of EpCAM-specific CAR in human induced pluripotent stem cells and their differentiation into NK cells |
title_full_unstemmed |
Targeted integration of EpCAM-specific CAR in human induced pluripotent stem cells and their differentiation into NK cells |
title_sort |
targeted integration of epcam-specific car in human induced pluripotent stem cells and their differentiation into nk cells |
publisher |
BioMed Central Ltd |
publishDate |
2022 |
url |
https://scholarbank.nus.edu.sg/handle/10635/233532 |
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1795301913031344128 |