Targeted integration of EpCAM-specific CAR in human induced pluripotent stem cells and their differentiation into NK cells

10.1186/s13287-021-02648-4

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Main Authors: Tang, Shin Yi, Zha, Shijun, Du, Zhicheng, Zeng, Jieming, Zhu, Detu, Luo, Yumei, Wang, Shu
Other Authors: BIOLOGICAL SCIENCES
Format: Article
Published: BioMed Central Ltd 2022
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Online Access:https://scholarbank.nus.edu.sg/handle/10635/233532
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spelling sg-nus-scholar.10635-2335322024-04-02T08:10:38Z Targeted integration of EpCAM-specific CAR in human induced pluripotent stem cells and their differentiation into NK cells Tang, Shin Yi Zha, Shijun Du, Zhicheng Zeng, Jieming Zhu, Detu Luo, Yumei Wang, Shu BIOLOGICAL SCIENCES Adeno-associated virus integration site 1 (AAVS1) Chimeric antigen receptors (CAR) Epithelial cell adhesion molecule (EpCAM) Genetic engineering Immunotherapy Induced pluripotent stem cells (iPSC) Natural killer cells (NK) NK differentiation Targeted integration Zinc finger nuclease (ZFN) 10.1186/s13287-021-02648-4 Stem Cell Research and Therapy 12 1 580 2022-10-26T09:00:44Z 2022-10-26T09:00:44Z 2021-11-21 Article Tang, Shin Yi, Zha, Shijun, Du, Zhicheng, Zeng, Jieming, Zhu, Detu, Luo, Yumei, Wang, Shu (2021-11-21). Targeted integration of EpCAM-specific CAR in human induced pluripotent stem cells and their differentiation into NK cells. Stem Cell Research and Therapy 12 (1) : 580. ScholarBank@NUS Repository. https://doi.org/10.1186/s13287-021-02648-4 1757-6512 https://scholarbank.nus.edu.sg/handle/10635/233532 Attribution 4.0 International https://creativecommons.org/licenses/by/4.0/ BioMed Central Ltd Scopus OA2021
institution National University of Singapore
building NUS Library
continent Asia
country Singapore
Singapore
content_provider NUS Library
collection ScholarBank@NUS
topic Adeno-associated virus integration site 1 (AAVS1)
Chimeric antigen receptors (CAR)
Epithelial cell adhesion molecule (EpCAM)
Genetic engineering
Immunotherapy
Induced pluripotent stem cells (iPSC)
Natural killer cells (NK)
NK differentiation
Targeted integration
Zinc finger nuclease (ZFN)
spellingShingle Adeno-associated virus integration site 1 (AAVS1)
Chimeric antigen receptors (CAR)
Epithelial cell adhesion molecule (EpCAM)
Genetic engineering
Immunotherapy
Induced pluripotent stem cells (iPSC)
Natural killer cells (NK)
NK differentiation
Targeted integration
Zinc finger nuclease (ZFN)
Tang, Shin Yi
Zha, Shijun
Du, Zhicheng
Zeng, Jieming
Zhu, Detu
Luo, Yumei
Wang, Shu
Targeted integration of EpCAM-specific CAR in human induced pluripotent stem cells and their differentiation into NK cells
description 10.1186/s13287-021-02648-4
author2 BIOLOGICAL SCIENCES
author_facet BIOLOGICAL SCIENCES
Tang, Shin Yi
Zha, Shijun
Du, Zhicheng
Zeng, Jieming
Zhu, Detu
Luo, Yumei
Wang, Shu
format Article
author Tang, Shin Yi
Zha, Shijun
Du, Zhicheng
Zeng, Jieming
Zhu, Detu
Luo, Yumei
Wang, Shu
author_sort Tang, Shin Yi
title Targeted integration of EpCAM-specific CAR in human induced pluripotent stem cells and their differentiation into NK cells
title_short Targeted integration of EpCAM-specific CAR in human induced pluripotent stem cells and their differentiation into NK cells
title_full Targeted integration of EpCAM-specific CAR in human induced pluripotent stem cells and their differentiation into NK cells
title_fullStr Targeted integration of EpCAM-specific CAR in human induced pluripotent stem cells and their differentiation into NK cells
title_full_unstemmed Targeted integration of EpCAM-specific CAR in human induced pluripotent stem cells and their differentiation into NK cells
title_sort targeted integration of epcam-specific car in human induced pluripotent stem cells and their differentiation into nk cells
publisher BioMed Central Ltd
publishDate 2022
url https://scholarbank.nus.edu.sg/handle/10635/233532
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