3-Chloro-3-methyl-2,6-diarylpiperidin-4-ones as Anti-Cancer Agents: Synthesis, Biological Evaluation, Molecular Docking, and In Silico ADMET Prediction

3-Chloro-3-methyl-2,6-diarylpiperidin-4-ones as Anti-Cancer Agents: Synthesis, Biological Evaluation, Molecular Docking, and In Silico ADMET Prediction

10.3390/biom12081093

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Bibliographic Details
Main Authors: Ramalingam, Arulraj, Mustafa, Nurulhuda, Chng, Wee Joo, Medimagh, Mouna, Sambandam, Sivakumar, Issaoui, Noureddine
Other Authors: MEDICINE
Format: Article
Language:English
Published: MDPI 2022
Subjects:
Science & Technology
Life Sciences & Biomedicine
Biochemistry & Molecular Biology
piperidin-4-ones
myeloma
leukemia
lymphoma
molecular docking calculation
computational ADMET
PROPERTY-BASED DESIGN
FACTOR XA INHIBITORS
DRUG ABSORPTION
KINASE
PYRROLIDIN-2-ONES
OPTIMIZATION
PIPERIDINES
SOLUBILITY
ACTIVATION
DISCOVERY
Online Access:https://scholarbank.nus.edu.sg/handle/10635/234468
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Institution: National University of Singapore
Language: English

Internet

https://scholarbank.nus.edu.sg/handle/10635/234468

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