METABOLIC ACTIVATION OF FIBROBLAST GROWTH FACTOR RECEPTOR INHIBITORS BY CYTOCHROME P450: MECHANISTIC INVESTIGATIONS INTO THE BIOCHEMICAL BASIS AND PHARMACOKINETIC IMPLICATIONS OF MECHANISM-BASED INACTIVATION
Ph.D
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| Format: | Theses and Dissertations |
| Language: | English |
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2022
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| Online Access: | https://scholarbank.nus.edu.sg/handle/10635/235764 |
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sg-nus-scholar.10635-2357642022-12-31T18:00:38Z METABOLIC ACTIVATION OF FIBROBLAST GROWTH FACTOR RECEPTOR INHIBITORS BY CYTOCHROME P450: MECHANISTIC INVESTIGATIONS INTO THE BIOCHEMICAL BASIS AND PHARMACOKINETIC IMPLICATIONS OF MECHANISM-BASED INACTIVATION TANG WEI TAT LLOYD PHARMACY Chun Yong, Eric Chan cytochrome P450, drug-drug interaction, fibroblast growth factor receptor inhibitor, metabolic activation, mechanism-based inactivation, Ph.D DOCTOR OF PHILOSOPHY (FOS) 2022-12-31T18:00:38Z 2022-12-31T18:00:38Z 2022-08-31 Thesis TANG WEI TAT LLOYD (2022-08-31). METABOLIC ACTIVATION OF FIBROBLAST GROWTH FACTOR RECEPTOR INHIBITORS BY CYTOCHROME P450: MECHANISTIC INVESTIGATIONS INTO THE BIOCHEMICAL BASIS AND PHARMACOKINETIC IMPLICATIONS OF MECHANISM-BASED INACTIVATION. ScholarBank@NUS Repository. https://scholarbank.nus.edu.sg/handle/10635/235764 0000-0001-7113-4397 en |
| institution |
National University of Singapore |
| building |
NUS Library |
| continent |
Asia |
| country |
Singapore Singapore |
| content_provider |
NUS Library |
| collection |
ScholarBank@NUS |
| language |
English |
| topic |
cytochrome P450, drug-drug interaction, fibroblast growth factor receptor inhibitor, metabolic activation, mechanism-based inactivation, |
| spellingShingle |
cytochrome P450, drug-drug interaction, fibroblast growth factor receptor inhibitor, metabolic activation, mechanism-based inactivation, TANG WEI TAT LLOYD METABOLIC ACTIVATION OF FIBROBLAST GROWTH FACTOR RECEPTOR INHIBITORS BY CYTOCHROME P450: MECHANISTIC INVESTIGATIONS INTO THE BIOCHEMICAL BASIS AND PHARMACOKINETIC IMPLICATIONS OF MECHANISM-BASED INACTIVATION |
| description |
Ph.D |
| author2 |
PHARMACY |
| author_facet |
PHARMACY TANG WEI TAT LLOYD |
| format |
Theses and Dissertations |
| author |
TANG WEI TAT LLOYD |
| author_sort |
TANG WEI TAT LLOYD |
| title |
METABOLIC ACTIVATION OF FIBROBLAST GROWTH FACTOR RECEPTOR INHIBITORS BY CYTOCHROME P450: MECHANISTIC INVESTIGATIONS INTO THE BIOCHEMICAL BASIS AND PHARMACOKINETIC IMPLICATIONS OF MECHANISM-BASED INACTIVATION |
| title_short |
METABOLIC ACTIVATION OF FIBROBLAST GROWTH FACTOR RECEPTOR INHIBITORS BY CYTOCHROME P450: MECHANISTIC INVESTIGATIONS INTO THE BIOCHEMICAL BASIS AND PHARMACOKINETIC IMPLICATIONS OF MECHANISM-BASED INACTIVATION |
| title_full |
METABOLIC ACTIVATION OF FIBROBLAST GROWTH FACTOR RECEPTOR INHIBITORS BY CYTOCHROME P450: MECHANISTIC INVESTIGATIONS INTO THE BIOCHEMICAL BASIS AND PHARMACOKINETIC IMPLICATIONS OF MECHANISM-BASED INACTIVATION |
| title_fullStr |
METABOLIC ACTIVATION OF FIBROBLAST GROWTH FACTOR RECEPTOR INHIBITORS BY CYTOCHROME P450: MECHANISTIC INVESTIGATIONS INTO THE BIOCHEMICAL BASIS AND PHARMACOKINETIC IMPLICATIONS OF MECHANISM-BASED INACTIVATION |
| title_full_unstemmed |
METABOLIC ACTIVATION OF FIBROBLAST GROWTH FACTOR RECEPTOR INHIBITORS BY CYTOCHROME P450: MECHANISTIC INVESTIGATIONS INTO THE BIOCHEMICAL BASIS AND PHARMACOKINETIC IMPLICATIONS OF MECHANISM-BASED INACTIVATION |
| title_sort |
metabolic activation of fibroblast growth factor receptor inhibitors by cytochrome p450: mechanistic investigations into the biochemical basis and pharmacokinetic implications of mechanism-based inactivation |
| publishDate |
2022 |
| url |
https://scholarbank.nus.edu.sg/handle/10635/235764 |
| _version_ |
1753801072376283136 |