METABOLIC ACTIVATION OF FIBROBLAST GROWTH FACTOR RECEPTOR INHIBITORS BY CYTOCHROME P450: MECHANISTIC INVESTIGATIONS INTO THE BIOCHEMICAL BASIS AND PHARMACOKINETIC IMPLICATIONS OF MECHANISM-BASED INACTIVATION

METABOLIC ACTIVATION OF FIBROBLAST GROWTH FACTOR RECEPTOR INHIBITORS BY CYTOCHROME P450: MECHANISTIC INVESTIGATIONS INTO THE BIOCHEMICAL BASIS AND PHARMACOKINETIC IMPLICATIONS OF MECHANISM-BASED INACTIVATION

Ph.D

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Bibliographic Details
Main Author: TANG WEI TAT LLOYD
Other Authors: PHARMACY
Format: Theses and Dissertations
Language:English
Published: 2022
Subjects:
cytochrome P450, drug-drug interaction, fibroblast growth factor receptor inhibitor, metabolic activation, mechanism-based inactivation,
Online Access:https://scholarbank.nus.edu.sg/handle/10635/235764
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Institution: National University of Singapore
Language: English
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