Epstein-Barr virus-induced ectopic CD137 expression helps nasopharyngeal carcinoma to escape immune surveillance and enables targeting by chimeric antigen receptors

10.1007/s00262-022-03183-8

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Main Authors: Prasad, Mukul, Ponnalagu, Sashigala, Zeng, Qun, Luu, Khang, Lang, Si Min, Wong, Hiu Yi, Cheng, Man Si, Wu, Meihui, Mallilankaraman, Karthik, Sobota, Radoslaw Mikolaj, Lim, Yan Ting, Wang, Loo Chien, Goh, Chuan Keng, Tay, Kai Xun Joshua, Loh, Kwok Seng, Wang, Cheng-, Lee, Wen-Hsien, Goh, Boon Cher, Lim, Chwee Ming, Schwarz, Herbert
Other Authors: MEDICINE
Format: Article
Language:English
Published: SPRINGER 2023
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Online Access:https://scholarbank.nus.edu.sg/handle/10635/239109
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Institution: National University of Singapore
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spelling sg-nus-scholar.10635-2391092024-11-15T16:29:57Z Epstein-Barr virus-induced ectopic CD137 expression helps nasopharyngeal carcinoma to escape immune surveillance and enables targeting by chimeric antigen receptors Prasad, Mukul Ponnalagu, Sashigala Zeng, Qun Luu, Khang Lang, Si Min Wong, Hiu Yi Cheng, Man Si Wu, Meihui Mallilankaraman, Karthik Sobota, Radoslaw Mikolaj Lim, Yan Ting Wang, Loo Chien Goh, Chuan Keng Tay, Kai Xun Joshua Loh, Kwok Seng Wang, Cheng- Lee, Wen-Hsien Goh, Boon Cher Lim, Chwee Ming Schwarz, Herbert MEDICINE PHYSIOLOGY MICROBIOLOGY AND IMMUNOLOGY DEAN'S OFFICE (DUKE-NUS MEDICAL SCHOOL) OTOLARYNGOLOGY BIOLOGICAL SCIENCES Assoc Prof Herbert Schwarz Science & Technology Life Sciences & Biomedicine Oncology Immunology Nasopharyngeal carcinoma Immune evasion Trogocytosis CD137 IL-6 IL-8 T-CELL RESPONSES COSTIMULATORY RECEPTOR THERAPEUTIC TARGET POOR-PROGNOSIS GROWTH-FACTOR 4-1BB ACTIVATION INDUCTION INTERLEUKIN-8 CD8(+) 10.1007/s00262-022-03183-8 CANCER IMMUNOLOGY IMMUNOTHERAPY 71 11 2583-2596 2023-05-02T08:41:43Z 2023-05-02T08:41:43Z 2022-03-17 2023-05-02T03:43:49Z Article Prasad, Mukul, Ponnalagu, Sashigala, Zeng, Qun, Luu, Khang, Lang, Si Min, Wong, Hiu Yi, Cheng, Man Si, Wu, Meihui, Mallilankaraman, Karthik, Sobota, Radoslaw Mikolaj, Lim, Yan Ting, Wang, Loo Chien, Goh, Chuan Keng, Tay, Kai Xun Joshua, Loh, Kwok Seng, Wang, Cheng-, Lee, Wen-Hsien, Goh, Boon Cher, Lim, Chwee Ming, Schwarz, Herbert (2022-03-17). Epstein-Barr virus-induced ectopic CD137 expression helps nasopharyngeal carcinoma to escape immune surveillance and enables targeting by chimeric antigen receptors. CANCER IMMUNOLOGY IMMUNOTHERAPY 71 (11) : 2583-2596. ScholarBank@NUS Repository. https://doi.org/10.1007/s00262-022-03183-8 0340-7004 1432-0851 https://scholarbank.nus.edu.sg/handle/10635/239109 en SPRINGER Elements
institution National University of Singapore
building NUS Library
continent Asia
country Singapore
Singapore
content_provider NUS Library
collection ScholarBank@NUS
language English
topic Science & Technology
Life Sciences & Biomedicine
Oncology
Immunology
Nasopharyngeal carcinoma
Immune evasion
Trogocytosis
CD137
IL-6
IL-8
T-CELL RESPONSES
COSTIMULATORY RECEPTOR
THERAPEUTIC TARGET
POOR-PROGNOSIS
GROWTH-FACTOR
4-1BB
ACTIVATION
INDUCTION
INTERLEUKIN-8
CD8(+)
spellingShingle Science & Technology
Life Sciences & Biomedicine
Oncology
Immunology
Nasopharyngeal carcinoma
Immune evasion
Trogocytosis
CD137
IL-6
IL-8
T-CELL RESPONSES
COSTIMULATORY RECEPTOR
THERAPEUTIC TARGET
POOR-PROGNOSIS
GROWTH-FACTOR
4-1BB
ACTIVATION
INDUCTION
INTERLEUKIN-8
CD8(+)
Prasad, Mukul
Ponnalagu, Sashigala
Zeng, Qun
Luu, Khang
Lang, Si Min
Wong, Hiu Yi
Cheng, Man Si
Wu, Meihui
Mallilankaraman, Karthik
Sobota, Radoslaw Mikolaj
Lim, Yan Ting
Wang, Loo Chien
Goh, Chuan Keng
Tay, Kai Xun Joshua
Loh, Kwok Seng
Wang, Cheng-
Lee, Wen-Hsien
Goh, Boon Cher
Lim, Chwee Ming
Schwarz, Herbert
Epstein-Barr virus-induced ectopic CD137 expression helps nasopharyngeal carcinoma to escape immune surveillance and enables targeting by chimeric antigen receptors
description 10.1007/s00262-022-03183-8
author2 MEDICINE
author_facet MEDICINE
Prasad, Mukul
Ponnalagu, Sashigala
Zeng, Qun
Luu, Khang
Lang, Si Min
Wong, Hiu Yi
Cheng, Man Si
Wu, Meihui
Mallilankaraman, Karthik
Sobota, Radoslaw Mikolaj
Lim, Yan Ting
Wang, Loo Chien
Goh, Chuan Keng
Tay, Kai Xun Joshua
Loh, Kwok Seng
Wang, Cheng-
Lee, Wen-Hsien
Goh, Boon Cher
Lim, Chwee Ming
Schwarz, Herbert
format Article
author Prasad, Mukul
Ponnalagu, Sashigala
Zeng, Qun
Luu, Khang
Lang, Si Min
Wong, Hiu Yi
Cheng, Man Si
Wu, Meihui
Mallilankaraman, Karthik
Sobota, Radoslaw Mikolaj
Lim, Yan Ting
Wang, Loo Chien
Goh, Chuan Keng
Tay, Kai Xun Joshua
Loh, Kwok Seng
Wang, Cheng-
Lee, Wen-Hsien
Goh, Boon Cher
Lim, Chwee Ming
Schwarz, Herbert
author_sort Prasad, Mukul
title Epstein-Barr virus-induced ectopic CD137 expression helps nasopharyngeal carcinoma to escape immune surveillance and enables targeting by chimeric antigen receptors
title_short Epstein-Barr virus-induced ectopic CD137 expression helps nasopharyngeal carcinoma to escape immune surveillance and enables targeting by chimeric antigen receptors
title_full Epstein-Barr virus-induced ectopic CD137 expression helps nasopharyngeal carcinoma to escape immune surveillance and enables targeting by chimeric antigen receptors
title_fullStr Epstein-Barr virus-induced ectopic CD137 expression helps nasopharyngeal carcinoma to escape immune surveillance and enables targeting by chimeric antigen receptors
title_full_unstemmed Epstein-Barr virus-induced ectopic CD137 expression helps nasopharyngeal carcinoma to escape immune surveillance and enables targeting by chimeric antigen receptors
title_sort epstein-barr virus-induced ectopic cd137 expression helps nasopharyngeal carcinoma to escape immune surveillance and enables targeting by chimeric antigen receptors
publisher SPRINGER
publishDate 2023
url https://scholarbank.nus.edu.sg/handle/10635/239109
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