Epstein-Barr virus-induced ectopic CD137 expression helps nasopharyngeal carcinoma to escape immune surveillance and enables targeting by chimeric antigen receptors

• Main Authors: Prasad, Mukul, Ponnalagu, Sashigala, Zeng, Qun, Luu, Khang, Lang, Si Min, Wong, Hiu Yi, Cheng, Man Si, Wu, Meihui, Mallilankaraman, Karthik, Sobota, Radoslaw Mikolaj, Lim, Yan Ting, Wang, Loo Chien, Goh, Chuan Keng, Tay, Kai Xun Joshua, Loh, Kwok Seng, Wang, Cheng-, Lee, Wen-Hsien, Goh, Boon Cher, Lim, Chwee Ming, Schwarz, Herbert
• Other Authors: MEDICINE
• Format: Article
• Language: English
• Published: SPRINGER 2023
• Subjects: Science & Technology; Life Sciences & Biomedicine; Oncology; Immunology; Nasopharyngeal carcinoma; Immune evasion; Trogocytosis; CD137; IL-6; IL-8; T-CELL RESPONSES; COSTIMULATORY RECEPTOR; THERAPEUTIC TARGET; POOR-PROGNOSIS; GROWTH-FACTOR; 4-1BB; ACTIVATION; INDUCTION; INTERLEUKIN-8; CD8(+)
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/239109
• Institution: National University of Singapore

10.1007/s00262-022-03183-8