CD28-CAR-T cell activation through FYN kinase signaling rather than LCK enhances therapeutic performance

• Main Authors: Wu, Ling, Brzostek, Joanna, Vale, Previtha Dawn Sakthi, Wei, Qianru, Koh, Clara KT, Ong, June Xu Hui, Wu, Liang-zhe, Tan, Jia Chi, Chua, Yen Leong, Yap, Jiawei, Song, Yuan, Tan, Vivian Jia Yi, Tan, Triscilla YY, Lai, Junyun, MacAry, Paul A, Gascoigne, Nicholas RJ
• Other Authors: BIOLOGICAL SCIENCES
• Format: Article
• Language: English
• Published: ELSEVIER 2023
• Subjects: Science & Technology; Life Sciences & Biomedicine; Cell Biology; Medicine, Research & Experimental; Research & Experimental Medicine; CHIMERIC ANTIGEN RECEPTOR; SRC-FAMILY KINASES; JURKAT T-CELLS; CD28 COSTIMULATION; TYROSINE KINASE; LYMPHOCYTES; INHIBITOR; SURVIVAL
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/239265
• Institution: National University of Singapore

10.1016/j.xcrm.2023.100917