Robust generation of human-chambered cardiac organoids from pluripotent stem cells for improved modelling of cardiovascular diseases

• Main Authors: Ho, Beatrice Xuan, Pang, Jeremy Kah Sheng, Chen, Ying, Loh, Yuin-Han, An, Omer, Yang, Henry He, Seshachalam, Veerabrahma Pratap, Koh, Judice LY, Chan, Woon-Khiong, Ng, Shi Yan, Soh, Boon Seng
• Other Authors: BIOLOGICAL SCIENCES
• Format: Article
• Language: English
• Published: BMC 2023
• Subjects: Science & Technology; Life Sciences & Biomedicine; Cell & Tissue Engineering; Cell Biology; Medicine, Research & Experimental; Research & Experimental Medicine; Cardiac progenitor; Chambered cardiac organoid; Disease modelling; Human pluripotent stem cells; Single-cell RNA sequencing; DIRECTED DIFFERENTIATION; TRANSCRIPTION FACTORS; HEART; HYPERTROPHY; PROGENITORS; PREVENTS; CULTURE
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/242578
• Institution: National University of Singapore

10.1186/s13287-022-03215-1