Reduced mitochondrial coenzyme Q10 levels in HepG2 cells treated with high-dose simvastatin: A possible role in statin-induced hepatotoxicity?

Reduced mitochondrial coenzyme Q10 levels in HepG2 cells treated with high-dose simvastatin: A possible role in statin-induced hepatotoxicity?

10.1016/j.taap.2007.05.013

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Main Authors: Tavintharan, S., Lim, S.C., Ong, C.N., Jeyaseelan, K., Sivakumar, M., Sum, C.F.
Other Authors: BIOCHEMISTRY
Format: Article
Published: 2011
Subjects:
Hepatotoxicity
Oxidative stress
Statins
Transaminitis
Ubiquinone
Online Access:http://scholarbank.nus.edu.sg/handle/10635/24481
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Institution: National University of Singapore
id sg-nus-scholar.10635-24481
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spelling sg-nus-scholar.10635-244812024-11-09T00:35:10Z Reduced mitochondrial coenzyme Q10 levels in HepG2 cells treated with high-dose simvastatin: A possible role in statin-induced hepatotoxicity? Tavintharan, S. Lim, S.C. Ong, C.N. Jeyaseelan, K. Sivakumar, M. Sum, C.F. BIOCHEMISTRY COMMUNITY,OCCUPATIONAL & FAMILY MEDICINE Hepatotoxicity Oxidative stress Statins Transaminitis Ubiquinone 10.1016/j.taap.2007.05.013 Toxicology and Applied Pharmacology 223 2 173-179 2011-07-25T07:16:41Z 2011-07-25T07:16:41Z 2007 Article Tavintharan, S., Lim, S.C., Ong, C.N., Jeyaseelan, K., Sivakumar, M., Sum, C.F. (2007). Reduced mitochondrial coenzyme Q10 levels in HepG2 cells treated with high-dose simvastatin: A possible role in statin-induced hepatotoxicity?. Toxicology and Applied Pharmacology 223 (2) : 173-179. ScholarBank@NUS Repository. https://doi.org/10.1016/j.taap.2007.05.013 0041008X 10960333 http://scholarbank.nus.edu.sg/handle/10635/24481 000249513400011 Scopus
institution National University of Singapore
building NUS Library
continent Asia
country Singapore
Singapore
content_provider NUS Library
collection ScholarBank@NUS
topic Hepatotoxicity
Oxidative stress
Statins
Transaminitis
Ubiquinone
spellingShingle Hepatotoxicity
Oxidative stress
Statins
Transaminitis
Ubiquinone
Tavintharan, S.
Lim, S.C.
Ong, C.N.
Jeyaseelan, K.
Sivakumar, M.
Sum, C.F.
Reduced mitochondrial coenzyme Q10 levels in HepG2 cells treated with high-dose simvastatin: A possible role in statin-induced hepatotoxicity?
description 10.1016/j.taap.2007.05.013
author2 BIOCHEMISTRY
author_facet BIOCHEMISTRY
Tavintharan, S.
Lim, S.C.
Ong, C.N.
Jeyaseelan, K.
Sivakumar, M.
Sum, C.F.
format Article
author Tavintharan, S.
Lim, S.C.
Ong, C.N.
Jeyaseelan, K.
Sivakumar, M.
Sum, C.F.
author_sort Tavintharan, S.
title Reduced mitochondrial coenzyme Q10 levels in HepG2 cells treated with high-dose simvastatin: A possible role in statin-induced hepatotoxicity?
title_short Reduced mitochondrial coenzyme Q10 levels in HepG2 cells treated with high-dose simvastatin: A possible role in statin-induced hepatotoxicity?
title_full Reduced mitochondrial coenzyme Q10 levels in HepG2 cells treated with high-dose simvastatin: A possible role in statin-induced hepatotoxicity?
title_fullStr Reduced mitochondrial coenzyme Q10 levels in HepG2 cells treated with high-dose simvastatin: A possible role in statin-induced hepatotoxicity?
title_full_unstemmed Reduced mitochondrial coenzyme Q10 levels in HepG2 cells treated with high-dose simvastatin: A possible role in statin-induced hepatotoxicity?
title_sort reduced mitochondrial coenzyme q10 levels in hepg2 cells treated with high-dose simvastatin: a possible role in statin-induced hepatotoxicity?
publishDate 2011
url http://scholarbank.nus.edu.sg/handle/10635/24481
_version_ 1821222821975556096

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