Electrostatic interactions at the five-fold axis alter heparin-binding phenotype and drive enterovirus A71 virulence in mice

• Main Authors: Tee, Han Kang, Tan, Chee Wah, Yogarajah, Thinesshwary, Lee, Michelle Hui Pheng, Chai, Hann Juang, Hanapi, Nur Aziah, Yusof, Siti R, Ong, Kien Chai, Lee, Vannajan Sanghiran, Sam, I-Ching, Chan, Yoke Fun
• Other Authors: DUKE-NUS MEDICAL SCHOOL
• Format: Article
• Language: English
• Published: PUBLIC LIBRARY SCIENCE 2024
• Subjects: Science & Technology; Life Sciences & Biomedicine; Microbiology; Parasitology; Virology; CAPSID PROTEIN VP1; SELECTIN GLYCOPROTEIN LIGAND-1; ENCEPHALITIS-VIRUS; MOUSE ADAPTATION; SULFATE BINDING; JAPANESE ENCEPHALITIS; E2 GLYCOPROTEIN; SINGLE MUTATION; MOUTH-DISEASE; 71 INFECTION
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/247888
• Institution: National University of Singapore

10.1371/journal.ppat.1007863