Ligand- and Coactivator-mediated Transactivation Function (AF2) of the Androgen Receptor Ligand-binding Domain Is Inhibited by the Cognate Hinge Region

Ligand- and Coactivator-mediated Transactivation Function (AF2) of the Androgen Receptor Ligand-binding Domain Is Inhibited by the Cognate Hinge Region

10.1074/jbc.M009916200

Saved in:

Bibliographic Details
Main Authors:	Wang, Q., Yong, E.L., Lu, J.
Other Authors:	OBSTETRICS & GYNAECOLOGY
Format:	Article
Published:	2013
Online Access:	http://scholarbank.nus.edu.sg/handle/10635/37398
Tags:	Add Tag No Tags, Be the first to tag this record!
Institution:	National University of Singapore

Similar Items

Androgen receptor transactivation domain and control of spermatogenesis
by: Yong, E.L., et al.
Published: (2013)

Human androgen receptor mutation disrupts ternary interactions between ligand, receptor domains, and the coactivator TIF2 (transcription intermediary factor 2)
by: Lim, J., et al.
Published: (2016)

Human androgen receptor mutation disrupts ternary interactions between ligand, receptor domains, and the coactivator TIF2 (transcription intermediary factor 2)
by: Lim, J., et al.
Published: (2013)

Partial androgen insensitivity and correlations with the predicted three dimensional structure of the androgen receptor ligand-binding domain
by: Yong, E.L., et al.
Published: (2013)

Azoospermia associated with a mutation in the ligand-binding domain of an androgen receptor displaying normal ligand binding, but defective trans- activation
by: Wang, Q., et al.
Published: (2013)

Analysis of the transactivation domain of the androgen receptor in patients with male infertility
by: Wang, Q., et al.
Published: (2013)

Filamin-A fragment localizes to the nucleus to regulate androgen receptor and coactivator functions
by: Loy, C.J., et al.
Published: (2013)

Androgen receptor mutations causing human androgen insensitivity syndromes show a key role of residue M807 in helix 8-helix 10 interactions and in receptor ligand-binding domain stability
by: Ong, Y.C., et al.
Published: (2013)

Ligand binding induces agonistic-like conformational adaptations in helix 12 of progesterone receptor ligand binding domain
by: Zheng, Liangzhen, et al.
Published: (2019)

Spreading of an anchorage-dependent cell on a selectively ligand-coated substrate mediated by receptor-ligand binding
by: Liu, P., et al.
Published: (2011)

Oligospermic infertility associated with an androgen receptor mutation that disrupts interdomain and coactivator (TIF2) interactions
by: Ghadessy, F.J., et al.
Published: (2013)

Progesterone receptor ligand binding domain : from conformational dynamics to drug discovery
by: Zheng, Liangzhen
Published: (2019)

Identification of SRC3/AIB1 as a preferred coactivator for hormone-activated androgen receptor
by: Zhou, X.E., et al.
Published: (2016)

CLiBE: A database of computed ligand binding energy for ligand-receptor complexes
by: Chen, X., et al.
Published: (2014)

Glutamate binding and conformational flexibility of ligand-binding domains are critical early determinants of efficient kainate receptor biogenesis
by: Martin B. Gill, et al.
Published: (2018)

Simulations of the spreading of a vesicle on a substrate surface mediated by receptor-ligand binding
by: Liu, P., et al.
Published: (2014)

Simulations of the spreading of a vesicle on a substrate surface mediated by receptor-ligand binding
by: Liu, P., et al.
Published: (2014)

Temperature dependence of estrogen binding: Importance of a subzone in the ligand binding domain of a novel piscine estrogen receptor
by: Tan, N.S., et al.
Published: (2014)

Ligand binding kinetics of cell surface receptors by microfluidic displacement
by: Ramji, R., et al.
Published: (2014)

Allosteric inhibition of the T cell receptor by a designed membrane ligand
by: Ye, Yujie, et al.
Published: (2024)

Modeling receptor-ligand mediated adhesion in nanoindentation of cells
by: Chunyu, Z., et al.
Published: (2014)

Modeling receptor-ligand mediated adhesion in nanoindentation of cells
by: Chunyu, Z., et al.
Published: (2014)

A computational modeling for micropipette-manipulated cell detachment from a substrate mediated by receptor-ligand binding
by: Cheng, Q.H., et al.
Published: (2014)

Screening for mutations in exons encoding the ligand-binding domain of the LDL receptor gene using PCR-CFLP and PCR-SSCP
by: Klai Upsorn Pongrapeeporn, et al.
Published: (2018)

Modelling ligand-receptor interactions: from multivalent to Linker-mediated
by: Xia, Xiuyang
Published: (2023)

Possible gene-gene interaction of KIR2DL4 with its cognate ligand HLA-G in modulating risk for preeclampsia
by: Tan, C.Y., et al.
Published: (2011)

Possible gene-gene interaction of KIR2DL4 with its cognate ligand HLA-G in modulating risk for preeclampsia
by: Tan, C.Y., et al.
Published: (2011)

Possible gene-gene interaction of KIR2DL4 with its cognate ligand HLA-G in modulating risk for preeclampsia
by: Tan, C.Y., et al.
Published: (2011)

Tyrosine phosphorylation of transcriptional coactivator WW-domain binding protein 2 regulates estrogen receptor α function in breast cancer via the Wnt pathway
by: Lim, S.K., et al.
Published: (2014)

Binding of canonical Wnt ligands to their receptor complexes occurs in ordered plasma membrane environments
by: Sezgin, E, et al.
Published: (2020)

Role of laminin and cognate receptors in cholangiocarcinoma cell migration
by: Kittiya Islam, et al.
Published: (2022)

The MDM2-binding region in the transactivation domain of p53 also acts as a Bcl-XL-binding motif
by: Xu, Huibin, et al.
Published: (2012)

Unique Structure and Dynamics of the EphA5 Ligand Binding Domain Mediate Its Binding Specificity as Revealed by X-ray Crystallography, NMR and MD Simulations
by: Huan, X., et al.
Published: (2014)

Lysine methylation of progesterone receptor at activation function 1 regulates both ligand-independent activity and ligand sensitivity of the receptor
by: Chung, Hwa Hwa, et al.
Published: (2018)

Studies on the interaction between Dengue virus and its cognate receptor
by: Sumalee Jindadamrongwech
Published: (2023)

The Crystal Structure of the Orphan Nuclear Receptor NR2E3/PNR Ligand Binding Domain Reveals a Dimeric Auto-Repressed Conformation
by: Tan M.H.E., et al.
Published: (2018)

Molecular mechanics of asialogycoprotetin receptor interactions with ligands
by: Chew, Lay Leng.
Published: (2008)

Phosphorylation of Src by phosphoinositide 3-kinase regulates beta-adrenergic receptor-mediated EGFR transactivation
by: Lewis J. Watson, et al.
Published: (2018)

Polioviral receptor binding ligand: a novel and safe peptide drug carrier from polioviral capsid
by: Manosroi J., et al.
Published: (2014)

Polioviral receptor binding ligand: A novel and safe peptide drug carrier from polioviral capsid
by: Jiradej Manosroi, et al.
Published: (2018)