Dynamic Kinetic Resolution for the Synthesis of Esters, Amides and Acids Using Lipases

• Main Authors: Fow, K.L., Zhu, Y., Chuah, G.K., Jaenicke, S., Van Nispen, S.F.G.M., Van Buijtenen, J., Vekemans, J.A.J.M., Meuldijk, J., Hulshof, L.A., Page, M., Blacker, J., Stirling, M., Ko, S., Kim, M., Park, J., Gastaldi, S., Gil, G., Bertrand, M.P., Kamaruddin, A.H., Hamzah, F., Truppo, M., Pollard, D., Moore, J., Devine, P.
• Other Authors: CHEMISTRY
• Format: Others
• Published: 2014
• Subjects: Bis(tetrafluorosuccinato)-bridged Ru(II) complex 1; Chemoenzymatic dynamic kinetic resolution of (S)-Ibuprofen; DKR method, applied to secondary alcohols; Dynamic kinetic resolution for ester, amide and acid synthesis using lipases; Dynamic kinetic resolution of 6,7-dimethoxy-1-methyl-1,2,3,4-tetrahydroisoquinoline; Dynamic kinetic resolution of primary amines with recyclable palladium nanocatalyst (Pd/AlO(OH)) for racemization; One-pot dynamic kinetic resolution (DKR) of (-)-1-phenylethanol lipase esterification in presence of zeolite beta; Procedure 1 - synthesis of (R)-1-phenylethyl octanoate; Procedure 2 - hydrolysis of (R)-1-phenylethyl octanoate; Synthesis of (R)-butyrate esters of secondary alcohols by DKR
• Online Access: http://scholarbank.nus.edu.sg/handle/10635/77523
• Institution: National University of Singapore

10.1002/9780470748589.ch4