Identification of a Novel Calotropis procera Protein That Can Suppress Tumor Growth in Breast Cancer through the Suppression of NF-κB Pathway

Identification of a Novel Calotropis procera Protein That Can Suppress Tumor Growth in Breast Cancer through the Suppression of NF-κB Pathway

10.1371/journal.pone.0048514

Saved in:

Bibliographic Details
Main Authors:	Samy, R.P., Rajendran, P., Li, F., Anandi, N.M., Stiles, B.G., Ignacimuthu, S., Sethi, G., Chow, V.T.K.
Other Authors:	PHYSICS
Format:	Article
Published:	2014
Online Access:	http://scholarbank.nus.edu.sg/handle/10635/96862
Tags:	Add Tag No Tags, Be the first to tag this record!
Institution:	National University of Singapore

Similar Items

Pilot study with regard to the wound healing activity of protein from calotropis procera (Ait.) R. Br.
by: Perumal Samy, R., et al.
Published: (2014)

Butein downregulates chemokine receptor CXCR4 expression and function through suppression of NF-κB activation in breast and pancreatic tumor cells
by: Chua, A.W.L., et al.
Published: (2014)

Potent Anti-Inflammatory Activity of Ursolic Acid, a Triterpenoid Antioxidant, Is Mediated through Suppression of NF-κB, AP-1 and NF-AT
by: Checker R., et al.
Published: (2018)

Anti-inflammatory effects of proanthocyanidin-rich red rice extract via suppression of MAPK, AP-1 and NF-κB pathways in Raw 264.7 macrophages
by: Limtrakul P., et al.
Published: (2017)

Cyperenoic acid suppresses osteoclast differentiation and delays bone loss in a senile osteoporosis mouse model by inhibiting non-canonical NF-κB pathway
by: Supatta Chawalitpong, et al.
Published: (2019)

Rumex dentatus inhibits cell proliferation, arrests cell cycle, and induces apoptosis in MDA-MB-231 cells through suppression of the NF-κB pathway
by: Batool, R, et al.
Published: (2020)

Role of NF-κB in tumorigenesis
by: Shanmugam, M.K., et al.
Published: (2014)

Anti-inflammatory effects of proanthocyanidin-rich red rice extract via suppression of MAPK, AP-1 and NF-κB pathways in Raw 264.7 macrophages
by: Pornngarm Limtrakul, et al.
Published: (2018)

Chitosan oligosaccharide suppresses tumor progression in a mouse model of colitis-associated colorectal cancer through AMPK activation and suppression of NF-κB and mTOR signaling
by: Tharinee Mattaveewong, et al.
Published: (2018)

Plant-based hydrocarbon esters from tragia involucrata possess antimicrobial and anti-inflammatory activities
by: Samy, R.P., et al.
Published: (2014)

Red jasmine rice extract suppresses genes associated with cartilage degradation in IL-1β-stimulated chondrosarcoma (SW1353) via blocking NF-κB pathway
by: Supitcha Thonghoi, et al.
Published: (2019)

Melatonin ameliorates methamphetamine-induced cognitive impairments by inhibiting neuroinflammation via suppression of the TLR4/MyD88/NFκB signaling pathway in the mouse hippocampus
by: Thit Lwin, et al.
Published: (2022)

Bromelain extract exerts antiarthritic effects via chondroprotection and the suppression of TNF-α-induced NF-κb and MAPK signaling
by: Peraphan Pothacharoen, et al.
Published: (2022)

A novel shogaol analog suppresses cancer cell invasion and inflammation, and displays cytoprotective effects through modulation of NF-κB and Nrf2-Keap1 signaling pathways
by: Gan, F.-F., et al.
Published: (2014)

1,5-Anhydro-d-fructose attenuates lipopolysaccharide-induced cytokine release via suppression of NF-κB p65 phosphorylation
by: Xiaojie Meng, et al.
Published: (2018)

Alpha-mangostin inhibits viral replication and suppresses nuclear factor kappa B (NF-κB)-mediated inflammation in dengue virus infection
by: Tarasuk M.
Published: (2023)

Suppressed NF-κB and sustained JNK activation contribute to the sensitization effect of parthenolide to TNF-α-induced apoptosis in human cancer cells
by: Zhang, S., et al.
Published: (2014)

Diosgenin, a steroidal saponin, inhibits STAT3 signaling pathway leading to suppression of proliferation and chemosensitization of human hepatocellular carcinoma cells
by: Li, F., et al.
Published: (2011)

Antiinflammatory activities of crebanine by inhibition of NF-κB and AP-1 activation through suppressing MAPKs and Akt signaling in LPS-induced RAW264.7 macrophages
by: Intayoung P., et al.
Published: (2017)

Artesunate activates the intrinsic apoptosis of HCT116 cells through the suppression of fatty acid synthesis and the NF-?B pathway
by: Chen, X, et al.
Published: (2020)

Association of Neuroprotective Effect of Di-O-Demethylcurcumin on Aβ<inf>25–35</inf>-Induced Neurotoxicity with Suppression of NF-κB and Activation of Nrf2
by: Pinkaew D., et al.
Published: (2017)

Targeting transcription factor NF-κB to overcome chemoresistance and radioresistance in cancer therapy
by: Li, F., et al.
Published: (2011)

Carrageenophyte Kappaphycus malesianus Inhibits Microglia-Mediated Neuroinflammation via Suppression of AKT/NF-kB and ERK Signaling Pathways
by: Nicole Jean-Yean Lai, -, et al.
Published: (2022)

Protocatechuic acid inhibits inflammatory responses in LPS-activated BV2 microglia via regulating SIRT1/NF-κB pathway contributed to the suppression of microglial activation-induced PC12 cell apoptosis
by: Chayanut Kaewmool, et al.
Published: (2020)

Antimicrobial proteins from snake venoms: Direct bacterial damage and activation of innate immunity against staphylococcus aureus skin infection
by: Samy, R.P., et al.
Published: (2014)

Crebanine, an aporphine alkaloid, sensitizes TNF-α-induced apoptosis and suppressed invasion of human lung adenocarcinoma cells A549 by blocking NF-κB-regulated gene products
by: Yodkeeree S., et al.
Published: (2014)

Association of Neuroprotective Effect of Di-O-Demethylcurcumin on Aβ<inf>25–35</inf>-Induced Neurotoxicity with Suppression of NF-κB and Activation of Nrf2
by: Decha Pinkaew, et al.
Published: (2018)

Antiinflammatory activities of crebanine by inhibition of NF-κB and AP-1 activation through suppressing MAPKs and Akt signaling in LPS-induced RAW264.7 macrophages
by: Pichanan Intayoung, et al.
Published: (2018)

Dicentrine potentiates TNF-α-induced apoptosis and suppresses invasion of a549 lung adenocarcinoma cells via modulation of nf-κb and ap-1 activation
by: Chanatip Ooppachai, et al.
Published: (2020)

Suppression of essential pro-inflammatory signaling pathways by natural agents for the therapy of multiple myeloma
by: Sikka, S., et al.
Published: (2014)

Gamma Radiation-Induced Disruption of Cellular Junctions in HUVECs Is Mediated through Affecting MAPK/NF- κB Inflammatory Pathways
by: Wang, H., et al.
Published: (2021)

Ursolic acid inhibits multiple cell survival pathways leading to suppression of growth of prostate cancer xenograft in nude mice
by: Shanmugam, M.K., et al.
Published: (2014)

AKR7A3 suppresses tumorigenicity and chemoresistance in hepatocellular carcinoma through attenuation of ERK, c-Jun and NF-?B signaling pathways
by: Chow, R.K.K, et al.
Published: (2020)

Melatonin Protects Methamphetamine-Induced Neuroinflammation Through NF-κB and Nrf2 Pathways in Glioma Cell Line
by: Jumnongprakhon P., et al.
Published: (2015)

Crebanine, an aporphine alkaloid, sensitizes TNF-α-induced apoptosis and suppressed invasion of human lung adenocarcinoma cells A549 by blocking NF-κB-regulated gene products
by: Supachai Yodkeeree, et al.
Published: (2018)

Cyanidin attenuates Aβ<inf>25-35</inf>-induced neuroinflammation by suppressing NF-κB activity downstream of TLR4/NOX4 in human neuroblastoma cells
by: Sarinthorn Thummayot, et al.
Published: (2018)

Crebanine, an aporphine alkaloid, sensitizes TNF-α-induced apoptosis and suppressed invasion of human lung adenocarcinoma cells A549 by blocking NF-κB-regulated gene products
by: Supachai Yodkeeree, et al.
Published: (2018)

Evidence for the involvement of the master transcription factor NF-κB in cancer initiation and progression
by: Puar, Y.R, et al.
Published: (2020)

First evidence that γ-tocotrienol inhibits the growth of human gastric cancer and chemosensitizes it to capecitabine in a xenograft mouse model through the modulation of NF-κB pathway
by: Manu, K.A., et al.
Published: (2014)

O-methylbulbocapnine and dicentrine suppress LPS-induced inflammatory response by blocking NF-κB and AP-1 activation through inhibiting MAPKs and Akt signaling in RAW264.7 macrophages
by: Supachai Yodkeeree, et al.
Published: (2018)