Protocatechuic acid inhibits inflammatory responses in LPS-activated BV2 microglia via regulating SIRT1/NF-κB pathway contributed to the suppression of microglial activation-induced PC12 cell apoptosis

• المؤلفون الرئيسيون: Chayanut Kaewmool, Prachya Kongtawelert, Thanyaluck Phitak, Peraphan Pothacharoen, Sasimol Udomruk
• التنسيق: دورية
• منشور في: 2020
• الموضوعات: Immunology and Microbiology; Medicine; Neuroscience
• الوصول للمادة أونلاين: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85078519526&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/68422
• المؤسسة: Chiang Mai University

© 2020 Elsevier B.V. SIRT1 exhibits inhibitory effects on microglial activation-induced neurodegeneration. Regulating SIRT1 may become a novel approach for curing neurodegenerative diseases. Protocatechuic acid (PA), a phenolic acid, has anti-neuroinflammatory effects. The effect of PA on SIRT1 in a...