On the Use of Surrogate Endpoints in Randomized Trials (with Discussion)

In a recent paper Day and Duffy proposed a strategy for designing a randomized trial of different breast cancer screening schedules. Their strategy was based on the use of predictors of mortality determined by patients' factors at diagnosis as surrogates for true mortality. On the basis of the...

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Bibliographic Details
Main Authors: Begg, C. B., Leung, Denis H. Y.
Format: text
Language:English
Published: Institutional Knowledge at Singapore Management University 2000
Subjects:
Online Access:https://ink.library.smu.edu.sg/soe_research/407
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Institution: Singapore Management University
Language: English