Testing of non-inferiority and superiority for three-arm clinincal studies with multiple experimental treatments

• المؤلفون الرئيسيون: ZHONG, JunJiang, KWONG, Koon Shing, CHEUNG, Siu Hung
• التنسيق: text
• اللغة: English
• منشور في: Institutional Knowledge at Singapore Management University 2016
• الموضوعات: Non-inferiority; superiority; three-arm trial; familywise error rate; assay sensitivity; Econometrics
• الوصول للمادة أونلاين: https://ink.library.smu.edu.sg/soe_research/1933; https://ink.library.smu.edu.sg/context/soe_research/article/2932/viewcontent/zhong_et_al_2016_testing_of_non_inferiority_and_superiority_for_three_arm_clinical_studies_with_multiple_experimental.pdf
• المؤسسة: Singapore Management University

The purpose of a non-inferiority trial is to assert the efficacy of an experimental treatment compared with a reference treatment by showing that the experimental treatment retains a substantial proportion of the efficacy of the reference treatment. Statistical methods have been developed to test mu...