Isotonic designs for phase I trials
The purpose of a phase I trial in cancer is to determine the level (dose) of the treatment under study that has an acceptable level of adverse effects. Although substantial progress has recently been made in this area using parametric approaches, the method that is widely used is based on treating s...
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Main Authors: | LEUNG, Denis H. Y., WANG, You-Gan |
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Format: | text |
Language: | English |
Published: |
Institutional Knowledge at Singapore Management University
2002
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Online Access: | https://ink.library.smu.edu.sg/soe_research/2155 https://ink.library.smu.edu.sg/context/soe_research/article/3155/viewcontent/IsotonicDesignsPhaseITrials_2001.pdf |
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Institution: | Singapore Management University |
Language: | English |
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