Mitochondrial calcium uniporter blocker prevents cardiac mitochondrial dysfunction induced by iron overload in thalassemic mice

Iron-overload induced cardiomyopathy is a major cause of morbidity and mortality in thalassemic patients. Previous studies suggest that cardiac mitochondrial dysfunction may be involved in the pathogenesis of cardiomyopathy in thalassemia. We tested the hypothesis that iron overload causes dysfuncti...

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Bibliographic Details
Main Authors: Kumfu S., Chattipakorn S., Fucharoen S., Chattipakorn N.
Format: Article
Language:English
Published: 2014
Online Access:http://www.scopus.com/inward/record.url?eid=2-s2.0-84865050953&partnerID=40&md5=743664c2f614cb60e10b419b5b55641b
http://www.ncbi.nlm.nih.gov/pubmed/22910858
http://cmuir.cmu.ac.th/handle/6653943832/1138
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Institution: Chiang Mai University
Language: English