Blockade of mitochondrial calcium uniporter prevents cardiac mitochondrial dysfunction caused by iron overload

• Main Authors: Sripetchwandee J., Kenknight S.B., Sanit J., Chattipakorn S., Chattipakorn N.
• Format: Article
• Language: English
• Published: 2014
• Online Access: http://www.scopus.com/inward/record.url?eid=2-s2.0-84892440533&partnerID=40&md5=ff63f28cafdf4d60b4ab564ac1c00be9; http://cmuir.cmu.ac.th/handle/6653943832/1181
• Institution: Chiang Mai University

Aim: Iron overload in the heart can lead to iron-overload cardiomyopathy and cardiac arrhythmia. In the past decades, growing evidence has suggested that cardiac mitochondrial dysfunction is associated with the development of cardiac dysfunction and lethal arrhythmias. Despite these facts, the effec...