Effects of sesamin on the biosynthesis of chondroitin sulfate proteoglycans in human articular chondrocytes in primary culture

• Main Authors: Pothacharoen P., Najarus S., Settakorn J., Mizumoto S., Sugahara K., Kongtawelert P.
• Format: Article
• Language: English
• Published: Kluwer Academic Publishers 2014
• Online Access: http://www.scopus.com/inward/record.url?eid=2-s2.0-84897495433&partnerID=40&md5=2a0bfb7c256d6323daec27ecf0347ac9; http://cmuir.cmu.ac.th/handle/6653943832/1705
• Institution: Chiang Mai University

Osteoarthritis (OA) is a degenerative joint disease that progressively causes a loss of joint functions and the impaired quality of life. The most significant event in OA is a high degree of degradation of articular cartilage accompanied by the loss of chondroitin sulfate-proteoglycans (CS-PGs). Rec...