Anti-inflammatory and analgesic activities of Mallotus spodocarpus Airy Shaw

The chloroform extract from the roots of Mallotus spodocarpus was investigated for anti-inflammatory and analgesic activities in animal models. In acute inflammatory models, the extract significantly inhibited ethyl phenylpropiolate-induced ear edema and carrageenin- and arachidonic acid-induced hin...

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Bibliographic Details
Main Authors: Intahphuak S., Panthong A., Kanjanapothi D., Taesotikul T., Krachangchaeng C., Reutrakul V.
Format: Article
Language:English
Published: 2014
Online Access:http://www.scopus.com/inward/record.url?eid=2-s2.0-0345862085&partnerID=40&md5=ebe57001554480b3acb8edc6581a5d38
http://www.ncbi.nlm.nih.gov/pubmed/14698511
http://cmuir.cmu.ac.th/handle/6653943832/1746
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Institution: Chiang Mai University
Language: English
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Summary:The chloroform extract from the roots of Mallotus spodocarpus was investigated for anti-inflammatory and analgesic activities in animal models. In acute inflammatory models, the extract significantly inhibited ethyl phenylpropiolate-induced ear edema and carrageenin- and arachidonic acid-induced hind paw edema in rats. In the chronic inflammatory model using the cotton pellet-induced granuloma in rats, the extract exhibited inhibitory activity on the formation of granuloma. The extract also elicited pronounced inhibitory effect on acetic acid-induced writhing response in mice in the analgesic test. The results obtained suggest marked anti-inflammatory and analgesic activity of the extract. © 2003 Elsevier Ireland Ltd. All rights reserved.