Anti-inflammatory and analgesic activities of Mallotus spodocarpus Airy Shaw
The chloroform extract from the roots of Mallotus spodocarpus was investigated for anti-inflammatory and analgesic activities in animal models. In acute inflammatory models, the extract significantly inhibited ethyl phenylpropiolate-induced ear edema and carrageenin- and arachidonic acid-induced hin...
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th-cmuir.6653943832-17462014-08-30T02:00:02Z Anti-inflammatory and analgesic activities of Mallotus spodocarpus Airy Shaw Intahphuak S. Panthong A. Kanjanapothi D. Taesotikul T. Krachangchaeng C. Reutrakul V. The chloroform extract from the roots of Mallotus spodocarpus was investigated for anti-inflammatory and analgesic activities in animal models. In acute inflammatory models, the extract significantly inhibited ethyl phenylpropiolate-induced ear edema and carrageenin- and arachidonic acid-induced hind paw edema in rats. In the chronic inflammatory model using the cotton pellet-induced granuloma in rats, the extract exhibited inhibitory activity on the formation of granuloma. The extract also elicited pronounced inhibitory effect on acetic acid-induced writhing response in mice in the analgesic test. The results obtained suggest marked anti-inflammatory and analgesic activity of the extract. © 2003 Elsevier Ireland Ltd. All rights reserved. 2014-08-30T02:00:02Z 2014-08-30T02:00:02Z 2004 Article 03788741 10.1016/j.jep.2003.09.026 14698511 JOETD http://www.scopus.com/inward/record.url?eid=2-s2.0-0345862085&partnerID=40&md5=ebe57001554480b3acb8edc6581a5d38 http://www.ncbi.nlm.nih.gov/pubmed/14698511 http://cmuir.cmu.ac.th/handle/6653943832/1746 English |
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The chloroform extract from the roots of Mallotus spodocarpus was investigated for anti-inflammatory and analgesic activities in animal models. In acute inflammatory models, the extract significantly inhibited ethyl phenylpropiolate-induced ear edema and carrageenin- and arachidonic acid-induced hind paw edema in rats. In the chronic inflammatory model using the cotton pellet-induced granuloma in rats, the extract exhibited inhibitory activity on the formation of granuloma. The extract also elicited pronounced inhibitory effect on acetic acid-induced writhing response in mice in the analgesic test. The results obtained suggest marked anti-inflammatory and analgesic activity of the extract. © 2003 Elsevier Ireland Ltd. All rights reserved. |
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Article |
author |
Intahphuak S. Panthong A. Kanjanapothi D. Taesotikul T. Krachangchaeng C. Reutrakul V. |
spellingShingle |
Intahphuak S. Panthong A. Kanjanapothi D. Taesotikul T. Krachangchaeng C. Reutrakul V. Anti-inflammatory and analgesic activities of Mallotus spodocarpus Airy Shaw |
author_facet |
Intahphuak S. Panthong A. Kanjanapothi D. Taesotikul T. Krachangchaeng C. Reutrakul V. |
author_sort |
Intahphuak S. |
title |
Anti-inflammatory and analgesic activities of Mallotus spodocarpus Airy Shaw |
title_short |
Anti-inflammatory and analgesic activities of Mallotus spodocarpus Airy Shaw |
title_full |
Anti-inflammatory and analgesic activities of Mallotus spodocarpus Airy Shaw |
title_fullStr |
Anti-inflammatory and analgesic activities of Mallotus spodocarpus Airy Shaw |
title_full_unstemmed |
Anti-inflammatory and analgesic activities of Mallotus spodocarpus Airy Shaw |
title_sort |
anti-inflammatory and analgesic activities of mallotus spodocarpus airy shaw |
publishDate |
2014 |
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http://www.scopus.com/inward/record.url?eid=2-s2.0-0345862085&partnerID=40&md5=ebe57001554480b3acb8edc6581a5d38 http://www.ncbi.nlm.nih.gov/pubmed/14698511 http://cmuir.cmu.ac.th/handle/6653943832/1746 |
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