Anti-inflammatory and analgesic activities of Mallotus spodocarpus Airy Shaw

The chloroform extract from the roots of Mallotus spodocarpus was investigated for anti-inflammatory and analgesic activities in animal models. In acute inflammatory models, the extract significantly inhibited ethyl phenylpropiolate-induced ear edema and carrageenin- and arachidonic acid-induced hin...

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Main Authors: Intahphuak S., Panthong A., Kanjanapothi D., Taesotikul T., Krachangchaeng C., Reutrakul V.
Format: Article
Language:English
Published: 2014
Online Access:http://www.scopus.com/inward/record.url?eid=2-s2.0-0345862085&partnerID=40&md5=ebe57001554480b3acb8edc6581a5d38
http://www.ncbi.nlm.nih.gov/pubmed/14698511
http://cmuir.cmu.ac.th/handle/6653943832/1746
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Institution: Chiang Mai University
Language: English
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spelling th-cmuir.6653943832-17462014-08-30T02:00:02Z Anti-inflammatory and analgesic activities of Mallotus spodocarpus Airy Shaw Intahphuak S. Panthong A. Kanjanapothi D. Taesotikul T. Krachangchaeng C. Reutrakul V. The chloroform extract from the roots of Mallotus spodocarpus was investigated for anti-inflammatory and analgesic activities in animal models. In acute inflammatory models, the extract significantly inhibited ethyl phenylpropiolate-induced ear edema and carrageenin- and arachidonic acid-induced hind paw edema in rats. In the chronic inflammatory model using the cotton pellet-induced granuloma in rats, the extract exhibited inhibitory activity on the formation of granuloma. The extract also elicited pronounced inhibitory effect on acetic acid-induced writhing response in mice in the analgesic test. The results obtained suggest marked anti-inflammatory and analgesic activity of the extract. © 2003 Elsevier Ireland Ltd. All rights reserved. 2014-08-30T02:00:02Z 2014-08-30T02:00:02Z 2004 Article 03788741 10.1016/j.jep.2003.09.026 14698511 JOETD http://www.scopus.com/inward/record.url?eid=2-s2.0-0345862085&partnerID=40&md5=ebe57001554480b3acb8edc6581a5d38 http://www.ncbi.nlm.nih.gov/pubmed/14698511 http://cmuir.cmu.ac.th/handle/6653943832/1746 English
institution Chiang Mai University
building Chiang Mai University Library
country Thailand
collection CMU Intellectual Repository
language English
description The chloroform extract from the roots of Mallotus spodocarpus was investigated for anti-inflammatory and analgesic activities in animal models. In acute inflammatory models, the extract significantly inhibited ethyl phenylpropiolate-induced ear edema and carrageenin- and arachidonic acid-induced hind paw edema in rats. In the chronic inflammatory model using the cotton pellet-induced granuloma in rats, the extract exhibited inhibitory activity on the formation of granuloma. The extract also elicited pronounced inhibitory effect on acetic acid-induced writhing response in mice in the analgesic test. The results obtained suggest marked anti-inflammatory and analgesic activity of the extract. © 2003 Elsevier Ireland Ltd. All rights reserved.
format Article
author Intahphuak S.
Panthong A.
Kanjanapothi D.
Taesotikul T.
Krachangchaeng C.
Reutrakul V.
spellingShingle Intahphuak S.
Panthong A.
Kanjanapothi D.
Taesotikul T.
Krachangchaeng C.
Reutrakul V.
Anti-inflammatory and analgesic activities of Mallotus spodocarpus Airy Shaw
author_facet Intahphuak S.
Panthong A.
Kanjanapothi D.
Taesotikul T.
Krachangchaeng C.
Reutrakul V.
author_sort Intahphuak S.
title Anti-inflammatory and analgesic activities of Mallotus spodocarpus Airy Shaw
title_short Anti-inflammatory and analgesic activities of Mallotus spodocarpus Airy Shaw
title_full Anti-inflammatory and analgesic activities of Mallotus spodocarpus Airy Shaw
title_fullStr Anti-inflammatory and analgesic activities of Mallotus spodocarpus Airy Shaw
title_full_unstemmed Anti-inflammatory and analgesic activities of Mallotus spodocarpus Airy Shaw
title_sort anti-inflammatory and analgesic activities of mallotus spodocarpus airy shaw
publishDate 2014
url http://www.scopus.com/inward/record.url?eid=2-s2.0-0345862085&partnerID=40&md5=ebe57001554480b3acb8edc6581a5d38
http://www.ncbi.nlm.nih.gov/pubmed/14698511
http://cmuir.cmu.ac.th/handle/6653943832/1746
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