Specific immune response and pathological findings in BALB/c mice inoculated with recombinat BCG expressing HIV-1 antigen

• Main Authors: Wiriyarat W., Sukpanichnant S., Sittisombut N., Balanchandra K., Promkhatkaew D., Butraporn R., Sutthent R., Boonlong J., Matsuo K., Honda M., Warachit P., Puthavathana P.
• Format: Article
• Language: English
• Published: 2014
• Online Access: http://www.scopus.com/inward/record.url?eid=2-s2.0-20344390518&partnerID=40&md5=3429b8702fdeebe5af4f12d65a5780a6; http://cmuir.cmu.ac.th/handle/6653943832/1936
• Institution: Chiang Mai University

Recombinant BCGs (rBCGs) containing extrachromosomal plasmids with different HIV-1 insert sequences: nef, env (V3J1 and E9Q), gag p17 or whole gag p55 were evaluated for their immunogenicity, safety and persistent infection in BALB/c mice. Animal injected with, rBCG-pIJKV3J1, rBCG-pSO gag p17 or rBC...